Effect of mango butter on the physicochemical properties of beeswax-Moringa seed oil-based oleogels for topical application
OBJECTIVE: The purpose of this research was to determine any connections between the characteristics of oleogels made of beeswax and the impact of mango butter.
METHODS: Oleogel was prepared through inverted tube methods, and optimized through oil binding capacity. Other evaluations like bright field and polarized microscopy, Fourier-transform infrared (FTIR) spectroscopy, crystallization kinetics, mechanical study, and X-ray diffractometry (XRD). The drug release kinetic studies and in vitro antibacterial studies were performed.
RESULTS: FTIR study reveals that the gelation process does not significantly alter the chemical composition of the individual components. Prepared gel exhibiting fluid-like behavior or composed of brittle networks is particularly vulnerable to disruptions in their network design. The incorporation of mango butter increases the drug permeation. In-vitro microbial efficacy study was found to be excellent.
CONCLUSION: The studies revealed that mango butter can be used to modify the physico-chemical properties of the oleogels.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2024 |
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Erschienen: |
2024 |
Enthalten in: |
Zur Gesamtaufnahme - year:2024 |
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Enthalten in: |
Drug development and industrial pharmacy - (2024) vom: 04. Apr., Seite 1-14 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Indu, Gourav Kumar [VerfasserIn] |
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Links: |
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Themen: |
Antimicrobial efficacy |
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Anmerkungen: |
Date Revised 04.04.2024 published: Print-Electronic Citation Status Publisher |
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doi: |
10.1080/03639045.2024.2334314 |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM370165616 |
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520 | |a OBJECTIVE: The purpose of this research was to determine any connections between the characteristics of oleogels made of beeswax and the impact of mango butter | ||
520 | |a METHODS: Oleogel was prepared through inverted tube methods, and optimized through oil binding capacity. Other evaluations like bright field and polarized microscopy, Fourier-transform infrared (FTIR) spectroscopy, crystallization kinetics, mechanical study, and X-ray diffractometry (XRD). The drug release kinetic studies and in vitro antibacterial studies were performed | ||
520 | |a RESULTS: FTIR study reveals that the gelation process does not significantly alter the chemical composition of the individual components. Prepared gel exhibiting fluid-like behavior or composed of brittle networks is particularly vulnerable to disruptions in their network design. The incorporation of mango butter increases the drug permeation. In-vitro microbial efficacy study was found to be excellent | ||
520 | |a CONCLUSION: The studies revealed that mango butter can be used to modify the physico-chemical properties of the oleogels | ||
650 | 4 | |a Journal Article | |
650 | 4 | |a Mango butter | |
650 | 4 | |a Moringa seed oil | |
650 | 4 | |a antimicrobial efficacy | |
650 | 4 | |a beeswax oleogel | |
650 | 4 | |a linezolid | |
650 | 4 | |a topical infections | |
700 | 1 | |a Habibullah, Sk |e verfasserin |4 aut | |
700 | 1 | |a Kumar Shaw, Tapan |e verfasserin |4 aut | |
700 | 1 | |a Mohanty, Biswaranjan |e verfasserin |4 aut | |
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