Effect of mango butter on the physicochemical properties of beeswax-Moringa seed oil-based oleogels for topical application

OBJECTIVE: The purpose of this research was to determine any connections between the characteristics of oleogels made of beeswax and the impact of mango butter.

METHODS: Oleogel was prepared through inverted tube methods, and optimized through oil binding capacity. Other evaluations like bright field and polarized microscopy, Fourier-transform infrared (FTIR) spectroscopy, crystallization kinetics, mechanical study, and X-ray diffractometry (XRD). The drug release kinetic studies and in vitro antibacterial studies were performed.

RESULTS: FTIR study reveals that the gelation process does not significantly alter the chemical composition of the individual components. Prepared gel exhibiting fluid-like behavior or composed of brittle networks is particularly vulnerable to disruptions in their network design. The incorporation of mango butter increases the drug permeation. In-vitro microbial efficacy study was found to be excellent.

CONCLUSION: The studies revealed that mango butter can be used to modify the physico-chemical properties of the oleogels.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - year:2024

Enthalten in:

Drug development and industrial pharmacy - (2024) vom: 04. Apr., Seite 1-14

Sprache:

Englisch

Beteiligte Personen:

Indu, Gourav Kumar [VerfasserIn]
Habibullah, Sk [VerfasserIn]
Kumar Shaw, Tapan [VerfasserIn]
Mohanty, Biswaranjan [VerfasserIn]

Links:

Volltext

Themen:

Antimicrobial efficacy
Beeswax oleogel
Journal Article
Linezolid
Mango butter
Moringa seed oil
Topical infections

Anmerkungen:

Date Revised 04.04.2024

published: Print-Electronic

Citation Status Publisher

doi:

10.1080/03639045.2024.2334314

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM370165616