Complete reduction surgery of a huge recurrent adult granulosa cell tumor after neoadjuvant chemotherapy
© The Author(s) under exclusive licence to The Japan Society of Clinical Oncology 2024. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law..
Adult granulosa cell tumors are rare, accounting for only 3-5% of all ovarian tumors. Adult granulosa cell tumors have late recurrences, for which complete resection is an effective option. We report a patient who underwent complete resection of a huge recurrent adult granulosa cell tumor after neoadjuvant chemotherapy. A 72-year-old woman underwent primary surgery for an adult granulosa cell tumor 19 years earlier. A huge recurrent tumor, 11 × 10 cm in size, was noted to elevate the hepatic hilum, inferior vena cava, and right renal vein. The recurrent tumor was too large to resect, thus paclitaxel and carboplatin were administered as neoadjuvant chemotherapy. The tumor shrank to 6 × 5 cm after 6 cycles of chemotherapy, then complete tumor extirpation with resection of the right kidney and temporary scission of inferior vena cava was performed. The patient was alive and well without evidence of a recurrence 1 y postoperatively. Paclitaxel and carboplatin, as neoadjuvant chemotherapy, might be an effective treatment option to achieve complete reduction surgery. This is the first report demonstrating the effectiveness of paclitaxel and carboplatin for huge recurrent adult granulosa cell tumor.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:13 |
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| Enthalten in: |
International cancer conference journal - 13(2024), 2 vom: 30. März, Seite 162-166 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Tokui, Hiroha [VerfasserIn] |
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| Links: |
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| Themen: |
Adult granulosa cell tumor |
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| Anmerkungen: |
Date Revised 26.03.2024 published: Electronic-eCollection Citation Status PubMed-not-MEDLINE |
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| doi: |
10.1007/s13691-024-00659-5 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| 520 | |a Adult granulosa cell tumors are rare, accounting for only 3-5% of all ovarian tumors. Adult granulosa cell tumors have late recurrences, for which complete resection is an effective option. We report a patient who underwent complete resection of a huge recurrent adult granulosa cell tumor after neoadjuvant chemotherapy. A 72-year-old woman underwent primary surgery for an adult granulosa cell tumor 19 years earlier. A huge recurrent tumor, 11 × 10 cm in size, was noted to elevate the hepatic hilum, inferior vena cava, and right renal vein. The recurrent tumor was too large to resect, thus paclitaxel and carboplatin were administered as neoadjuvant chemotherapy. The tumor shrank to 6 × 5 cm after 6 cycles of chemotherapy, then complete tumor extirpation with resection of the right kidney and temporary scission of inferior vena cava was performed. The patient was alive and well without evidence of a recurrence 1 y postoperatively. Paclitaxel and carboplatin, as neoadjuvant chemotherapy, might be an effective treatment option to achieve complete reduction surgery. This is the first report demonstrating the effectiveness of paclitaxel and carboplatin for huge recurrent adult granulosa cell tumor | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Adult granulosa cell tumor | |
| 650 | 4 | |a Late recurrence | |
| 650 | 4 | |a Neoadjuvant chemotherapy | |
| 700 | 1 | |a Yahata, Hideaki |e verfasserin |4 aut | |
| 700 | 1 | |a Okabe, Yasuhiro |e verfasserin |4 aut | |
| 700 | 1 | |a Magarifuchi, Naomi |e verfasserin |4 aut | |
| 700 | 1 | |a Maenohara, Shoji |e verfasserin |4 aut | |
| 700 | 1 | |a Hachisuga, Kazuhisa |e verfasserin |4 aut | |
| 700 | 1 | |a Tomonobe, Hiroshi |e verfasserin |4 aut | |
| 700 | 1 | |a Kodama, Keisuke |e verfasserin |4 aut | |
| 700 | 1 | |a Yagi, Hiroshi |e verfasserin |4 aut | |
| 700 | 1 | |a Yasunaga, Masafumi |e verfasserin |4 aut | |
| 700 | 1 | |a Onoyama, Ichiro |e verfasserin |4 aut | |
| 700 | 1 | |a Asanoma, Kazuo |e verfasserin |4 aut | |
| 700 | 1 | |a Oda, Yoshinao |e verfasserin |4 aut | |
| 700 | 1 | |a Nakamura, Masafumi |e verfasserin |4 aut | |
| 700 | 1 | |a Kato, Kiyoko |e verfasserin |4 aut | |
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