Matching on Generalized Propensity Scores with Continuous Exposures
In the context of a binary treatment, matching is a well-established approach in causal inference. However, in the context of a continuous treatment or exposure, matching is still underdeveloped. We propose an innovative matching approach to estimate an average causal exposure-response function under the setting of continuous exposures that relies on the generalized propensity score (GPS). Our approach maintains the following attractive features of matching: a) clear separation between the design and the analysis; b) robustness to model misspecification or to the presence of extreme values of the estimated GPS; c) straightforward assessments of covariate balance. We first introduce an assumption of identifiability, called local weak unconfoundedness. Under this assumption and mild smoothness conditions, we provide theoretical guarantees that our proposed matching estimator attains point-wise consistency and asymptotic normality. In simulations, our proposed matching approach outperforms existing methods under settings with model misspecification or in the presence of extreme values of the estimated GPS. We apply our proposed method to estimate the average causal exposure-response function between long-term PM2.5 exposure and all-cause mortality among 68.5 million Medicare enrollees, 2000-2016. We found strong evidence of a harmful effect of long-term PM2.5 exposure on mortality. Code for the proposed matching approach is provided in the CausalGPS R package, which is available on CRAN and provides a computationally efficient implementation.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:119 |
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| Enthalten in: |
Journal of the American Statistical Association - 119(2024), 545 vom: 01., Seite 757-772 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Wu, Xiao [VerfasserIn] |
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| Links: |
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| Themen: |
Causal Inference |
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| Anmerkungen: |
Date Revised 27.03.2024 published: Print-Electronic Citation Status PubMed-not-MEDLINE |
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| doi: |
10.1080/01621459.2022.2144737 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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NLM370138147 |
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| 520 | |a In the context of a binary treatment, matching is a well-established approach in causal inference. However, in the context of a continuous treatment or exposure, matching is still underdeveloped. We propose an innovative matching approach to estimate an average causal exposure-response function under the setting of continuous exposures that relies on the generalized propensity score (GPS). Our approach maintains the following attractive features of matching: a) clear separation between the design and the analysis; b) robustness to model misspecification or to the presence of extreme values of the estimated GPS; c) straightforward assessments of covariate balance. We first introduce an assumption of identifiability, called local weak unconfoundedness. Under this assumption and mild smoothness conditions, we provide theoretical guarantees that our proposed matching estimator attains point-wise consistency and asymptotic normality. In simulations, our proposed matching approach outperforms existing methods under settings with model misspecification or in the presence of extreme values of the estimated GPS. We apply our proposed method to estimate the average causal exposure-response function between long-term PM2.5 exposure and all-cause mortality among 68.5 million Medicare enrollees, 2000-2016. We found strong evidence of a harmful effect of long-term PM2.5 exposure on mortality. Code for the proposed matching approach is provided in the CausalGPS R package, which is available on CRAN and provides a computationally efficient implementation | ||
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| 700 | 1 | |a Braun, Danielle |e verfasserin |4 aut | |
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