A case of Holmes tremor in which 123I-IMP SPECT and MRI findings suggest damage to the cerebellothalamic tract and the dentato-rubro-olivary pathway

A 75-year-old woman was referred to our department in October 2022 with ataxia and involuntary movements of the right upper and lower limbs. She had experienced a left pontine hemorrhage in March 2021, which was managed conservatively. However, she had residual right-sided hemiplegia. In addition, she had cerebellar ataxia and a 2 ‍Hz resting tremor of the right upper and lower limbs, which was enhanced while maintaining posture and contemplation. Based on her history, and the findings of MRI and nuclear medicine imaging, we diagnosed the patient with Holmes tremor due to pontine hemorrhage. Holmes tremor is a rare movement disorder secondary to brainstem and thalamic lesions, characterized by a unilateral low-frequency tremor. In this case, 123I-IMP SPECT and MRI shows damage to the cerebellothalamic tract and dentaro-rubro-olivary pathway.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:64

Enthalten in:

Rinsho shinkeigaku = Clinical neurology - 64(2024), 4 vom: 24. Apr., Seite 280-285

Sprache:

Japanisch

Beteiligte Personen:

Ishimaru, Tomoki [VerfasserIn]
Nunomura, Sumire [VerfasserIn]
Wakita, Masahiro [VerfasserIn]
Ura, Shigehisa [VerfasserIn]

Links:

Volltext

Themen:

C2A5X08042
Case Reports
Cerebellothalamic tract
Dentato-rubro-olivary pathway
English Abstract
Holmes tremor
Iodine Radioisotopes
Iofetamine
Journal Article
Nigrostriatal pathway

Anmerkungen:

Date Completed 24.04.2024

Date Revised 24.04.2024

published: Print-Electronic

Citation Status MEDLINE

doi:

10.5692/clinicalneurol.cn-001913

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM370124774