Otologic disease trends in Japan post-COVID-19 outbreak : A retrospective time-series analysis

Copyright © 2024. Published by Elsevier B.V..

OBJECTIVE: To evaluate the potential impact of coronavirus disease 2019 (COVID-19) and vaccinations on otologic diseases, including facial nerve paralysis (including Ramsay Hunt syndrome), vestibular neuritis, sudden sensorineural hearing loss, and Meniere's disease.

METHODS: In this retrospective study, we conducted a time-series analysis employing a causal impact algorithm on a large-scale inpatient database in Japan. We compared the actual number of hospitalized patients with otologic diseases to two predictions: one without any covariates and another with a covariate accounting for the reduction in the number of hospitalized patients due to lockdown measures. Additionally, we performed Granger causality tests to ensure the robustness of our findings.

RESULTS: No significant increase was noted in the number of hospitalized patients with otologic diseases following the onset of the COVID-19 pandemic in the causal impact analysis. Similarly, no notable surge was observed in hospitalizations for these diseases following the introduction of the COVID-19 vaccine. The Granger causality tests results aligned with the causal impact analysis findings.

CONCLUSION: Our findings indicate that COVID-19 and vaccinations had minimal discernible effects on hospitalization of patients with otologic diseases, suggesting that otologic diseases may not be significantly impacted by COVID-19 and vaccinations, which could have implications for public health policies and the allocation of healthcare resources during a pandemic. Further research and monitoring of long-term effects are warranted to validate these findings and guide healthcare decision-making.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:51

Enthalten in:

Auris, nasus, larynx - 51(2024), 3 vom: 23. März, Seite 525-530

Sprache:

Englisch

Beteiligte Personen:

Kondo, Keisuke [VerfasserIn]
Honda, Keiji [VerfasserIn]
Goshima, Keiichi [VerfasserIn]
Inoue, Norihiko [VerfasserIn]
Shinjo, Daisuke [VerfasserIn]
Tsutsumi, Takeshi [VerfasserIn]
Fushimi, Kiyohide [VerfasserIn]

Links:

Volltext

Themen:

COVID 19
Herpes zoster
Journal Article
Ramsay Hunt syndrome
Time series analysis
Vaccine

Anmerkungen:

Date Revised 24.03.2024

published: Print-Electronic

Citation Status Publisher

doi:

10.1016/j.anl.2024.01.004

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM370119231