Clinical application of real-time continuous glucose monitoring system during postoperative enteral nutrition therapy in esophageal cancer patients

© 2024 American Society for Parenteral and Enteral Nutrition..

BACKGROUND: Enteral nutrition (EN) support therapy increases the risk of abnormal blood glucose (BG). The aim of this study is to evaluate the clinical value of a real-time continuous glucose monitoring (rt-CGM) system in BG monitoring during postoperative EN support therapy in patients with esophageal cancer.

METHODS: Patients without diabetes mellitus (DM) with esophageal cancer who planned to receive postoperative EN were enrolled. With the self-monitoring of BG value as the reference BG, the accuracy of rt-CGM was evaluated by the mean absolute relative difference (MARD) value, correlation efficient, agreement analysis, and Parkes and Clarke error grid plot. Finally, paired t tests were used to compare the differences in glucose fluctuations between EN and non-EN days and slow and fast days.

RESULTS: The total MARD value of the rt-CGM system was 13.53%. There was a high correlation between interstitial glucose and fingertip capillary BG (consistency correlation efficient = 0.884 [95% confidence interval, 0.874-0.894]). Results of 15/15%, 20/20%, 30/30% agreement analysis were 58.51%, 84.71%, and 99.65%, respectively. The Parkes and Clarke error grid showed that the proportion of the A and B regions were 100% and 99.94%, respectively. The glucose fluctuations on EN days vs non-EN days and on fast days vs slow days were large, and the difference was statistically significant (P < 0.001).

CONCLUSION: The rt-CGM system achieved clinical accuracy and can be used as a new option for glucose monitoring during postoperative EN therapy. The magnitude of glucose fluctuation during EN therapy remains large, even in the postoperative population without DM.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - year:2024

Enthalten in:

Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition - (2024) vom: 24. März

Sprache:

Englisch

Beteiligte Personen:

Zhang, Ranran [VerfasserIn]
Wu, Ying [VerfasserIn]
Xv, Rui [VerfasserIn]
Wang, Wei [VerfasserIn]
Zhang, Lei [VerfasserIn]
Wang, Ansheng [VerfasserIn]
Li, Min [VerfasserIn]
Jiang, Wei [VerfasserIn]
Jin, Guoxi [VerfasserIn]
Hu, Xiaolei [VerfasserIn]

Links:

Volltext

Themen:

Enteral nutrition
Esophageal cancer
Glucose fluctuation
Journal Article
Real‐time continuous glucose monitoring
Self‐monitoring of blood glucose

Anmerkungen:

Date Revised 24.03.2024

published: Print-Electronic

Citation Status Publisher

doi:

10.1002/ncp.11143

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM370115864