The successful treatment of mpox with brincidofovir in renal transplant recipients-a report of 2 cases
Copyright © 2024 The Author(s). Published by Elsevier Ltd.. All rights reserved..
An mpox outbreak was declared in July 2022 by the world health organization (WHO). It causes a mild self-limiting disease however; in immunosuppressed hosts, it tends to cause severe disseminated infection. Most cases of mpox in sold organ transplant (SOT) recipients reported in the literature were treated with tecovirimat. Here we report two cases of severe disseminated mpox infection in renal transplant recipients that were successfully treated with brincidofovir. Both patients were discharged from the hospital with no immediate significant side effects from brincidofovir reported until the submission of this report.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:143 |
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| Enthalten in: |
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 143(2024) vom: 21. März, Seite 107015 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Alameer, Reem M [VerfasserIn] |
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| Links: |
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| Themen: |
Brincidofovir |
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| Anmerkungen: |
Date Revised 22.04.2024 published: Print-Electronic Citation Status Publisher |
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| doi: |
10.1016/j.ijid.2024.107015 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| 520 | |a An mpox outbreak was declared in July 2022 by the world health organization (WHO). It causes a mild self-limiting disease however; in immunosuppressed hosts, it tends to cause severe disseminated infection. Most cases of mpox in sold organ transplant (SOT) recipients reported in the literature were treated with tecovirimat. Here we report two cases of severe disseminated mpox infection in renal transplant recipients that were successfully treated with brincidofovir. Both patients were discharged from the hospital with no immediate significant side effects from brincidofovir reported until the submission of this report | ||
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| 700 | 1 | |a Shendi, Ali M |e verfasserin |4 aut | |
| 700 | 1 | |a Almaghrabi, Reem S |e verfasserin |4 aut | |
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