Biosafety aspects of RNAi-based pests control
© 2024 Society of Chemical Industry..
While the overuse of classical chemical pesticides has had a detrimental impact on the environment and human health, the discovery of RNA interference (RNAi) offered the opportunity to develop new and sustainable approaches for pest management. RNAi is a naturally occurring regulation and defense mechanism that can be exploited to effectively protect crops by silencing key genes affecting the growth, development, behavior or fecundity of pests. However, as with all technologies, there is a range of potential risks and challenges associated with the application of RNAi, such as dsRNA stability, the potential for off-target effects, the safety of non-target organisms, and other application challenges. A better understanding of the molecular mechanisms involved in RNAi and in-depth discussion and analysis of these associated safety risks, is required to limit or mitigate potential adverse effects. © 2024 Society of Chemical Industry.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2024 |
|---|---|
| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - year:2024 |
|---|---|
| Enthalten in: |
Pest management science - (2024) vom: 23. März |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Chen, Yimeng [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Biosafety |
|---|
| Anmerkungen: |
Date Revised 05.04.2024 published: Print-Electronic Citation Status Publisher |
|---|
| doi: |
10.1002/ps.8098 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM370098919 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM370098919 | ||
| 003 | DE-627 | ||
| 005 | 20240405233939.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 240324s2024 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1002/ps.8098 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1366.xml |
| 035 | |a (DE-627)NLM370098919 | ||
| 035 | |a (NLM)38520331 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Chen, Yimeng |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Biosafety aspects of RNAi-based pests control |
| 264 | 1 | |c 2024 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Revised 05.04.2024 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status Publisher | ||
| 520 | |a © 2024 Society of Chemical Industry. | ||
| 520 | |a While the overuse of classical chemical pesticides has had a detrimental impact on the environment and human health, the discovery of RNA interference (RNAi) offered the opportunity to develop new and sustainable approaches for pest management. RNAi is a naturally occurring regulation and defense mechanism that can be exploited to effectively protect crops by silencing key genes affecting the growth, development, behavior or fecundity of pests. However, as with all technologies, there is a range of potential risks and challenges associated with the application of RNAi, such as dsRNA stability, the potential for off-target effects, the safety of non-target organisms, and other application challenges. A better understanding of the molecular mechanisms involved in RNAi and in-depth discussion and analysis of these associated safety risks, is required to limit or mitigate potential adverse effects. © 2024 Society of Chemical Industry | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Review | |
| 650 | 4 | |a RNAi | |
| 650 | 4 | |a RNAi‐based pesticides | |
| 650 | 4 | |a biosafety | |
| 650 | 4 | |a host‐induced gene silencing (HIGS) | |
| 650 | 4 | |a risk assessment | |
| 650 | 4 | |a spray‐induced gene silencing (SIGS) | |
| 700 | 1 | |a De Schutter, Kristof |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Pest management science |d 2001 |g (2024) vom: 23. März |w (DE-627)NLM112799132 |x 1526-4998 |7 nnns |
| 773 | 1 | 8 | |g year:2024 |g day:23 |g month:03 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1002/ps.8098 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |j 2024 |b 23 |c 03 | ||