Aflatoxins in maize flour produced in Mozambique and its risk assessment
This study investigated the occurrence of aflatoxins (B1, B2, G1, and G2) in maize flour produced in Mozambique and to assess the associated carcinogenic risk. At different opportunities, 30 samples of maize flour were collected in five flour processing factories. These were determined by high-performance liquid chromatography (HPLC) with fluorescence detection. AFB1 concentrations ranged from 0.25 to 0.33 μg kg-1. The levels of total aflatoxins ranged from 0.55 to 1.05 μg kg-1, with a mean of 0.89 μg kg-1, for which maximum limits (MLs) are 10 and 4 μg kg-1 for Mozambique and the European Union, respectively. The calculated Margin of Exposure (MOE) for men and women was 243 and 231, respectively, so several folds below the risk cut-off level, indicating that consumption of such maize flour poses a potential risk of hepatocarcinoma related to aflatoxin exposure due to high intake of this food, a staple diet in most African countries.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2024 |
|---|---|
| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - year:2024 |
|---|---|
| Enthalten in: |
Food additives & contaminants. Part B, Surveillance - (2024) vom: 22. März, Seite 1-9 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Martinho, Martinho Gamas Dinis [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Journal Article |
|---|
| Anmerkungen: |
Date Revised 22.03.2024 published: Print-Electronic Citation Status Publisher |
|---|
| doi: |
10.1080/19393210.2024.2331630 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM370049772 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM370049772 | ||
| 003 | DE-627 | ||
| 005 | 20240323002120.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 240323s2024 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1080/19393210.2024.2331630 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1341.xml |
| 035 | |a (DE-627)NLM370049772 | ||
| 035 | |a (NLM)38515402 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Martinho, Martinho Gamas Dinis |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Aflatoxins in maize flour produced in Mozambique and its risk assessment |
| 264 | 1 | |c 2024 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Revised 22.03.2024 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status Publisher | ||
| 520 | |a This study investigated the occurrence of aflatoxins (B1, B2, G1, and G2) in maize flour produced in Mozambique and to assess the associated carcinogenic risk. At different opportunities, 30 samples of maize flour were collected in five flour processing factories. These were determined by high-performance liquid chromatography (HPLC) with fluorescence detection. AFB1 concentrations ranged from 0.25 to 0.33 μg kg-1. The levels of total aflatoxins ranged from 0.55 to 1.05 μg kg-1, with a mean of 0.89 μg kg-1, for which maximum limits (MLs) are 10 and 4 μg kg-1 for Mozambique and the European Union, respectively. The calculated Margin of Exposure (MOE) for men and women was 243 and 231, respectively, so several folds below the risk cut-off level, indicating that consumption of such maize flour poses a potential risk of hepatocarcinoma related to aflatoxin exposure due to high intake of this food, a staple diet in most African countries | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Mycotoxins | |
| 650 | 4 | |a maize products | |
| 650 | 4 | |a mozambique, food security | |
| 650 | 4 | |a risk assessment | |
| 700 | 1 | |a Rocha, Andrea Rebouças |e verfasserin |4 aut | |
| 700 | 1 | |a Dos Santos, Nathália Ribeiro |e verfasserin |4 aut | |
| 700 | 1 | |a de Jesus, Vinícius Silva Pitanga |e verfasserin |4 aut | |
| 700 | 1 | |a Gomes Júnior, Erival Amorim |e verfasserin |4 aut | |
| 700 | 1 | |a Menezes-Filho, José Antonio |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Food additives & contaminants. Part B, Surveillance |d 2008 |g (2024) vom: 22. März, Seite 1-9 |w (DE-627)NLM208086404 |x 1939-3229 |7 nnns |
| 773 | 1 | 8 | |g year:2024 |g day:22 |g month:03 |g pages:1-9 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1080/19393210.2024.2331630 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |j 2024 |b 22 |c 03 |h 1-9 | ||