Epidemiological characteristics of Epstein-Barr virus infection in children and distribution of disease spectrum in hospitalized patients in shandong province

© 2024 The Authors. Journal of Medical Virology published by Wiley Periodicals LLC..

This study aims to investigate the epidemiological characteristics of Epstein-Barr virus (EBV) infection in children and the distribution of disease spectrum in hospitalized patients in Shandong Province. A retrospective analysis was conducted on the clinical data of children with EBV infection admitted to hospitals in Shandong Province from January 2022 to December 2022. The epidemiological characteristics, including age, gender, and clinical manifestations, were analyzed. The detection rate of EBV antibodies and the seropositivity rates of different antibodies were also examined. A total of 7124 children with EBV infection were included in this study, with an average age of 7.5 years. The male-to-female ratio was 1.43:1. Among the patients, the positive detection rate of EBV antibodies was 78.40%. The seropositivity rate of Epstein-Barr viral capsid antigen-Immunoglobin G antibodies was 57.09%. The highest incidence of EBV infection was observed in the age group 36-72 months. The urban positive rate was higher than that in rural areas. EBV infection in children in Shandong Province exhibits specific epidemiological characteristics, with a higher incidence in the age group of 36-72 months. Fever, sore throat, and fatigue are the main clinical manifestations. The detection rate of EBV antibodies is relatively high among hospitalized patients. These findings provide valuable information for controlling the transmission of children with suspected Epstein-Barr virus infection.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:96

Enthalten in:

Journal of medical virology - 96(2024), 3 vom: 22. März, Seite e29561

Sprache:

Englisch

Beteiligte Personen:

Wu, Dan [VerfasserIn]
Wang, Juan [VerfasserIn]
Zeng, Qian [VerfasserIn]
Wang, Ling [VerfasserIn]
Lv, Xin [VerfasserIn]

Links:

Volltext

Themen:

Antibodies, Viral
Antibody model
Epstein‐Barr virus antibody
Journal Article
Primary infection

Anmerkungen:

Date Completed 22.03.2024

Date Revised 22.03.2024

published: Print

Citation Status MEDLINE

doi:

10.1002/jmv.29561

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM370011139