Topology optimization of embracing fixator considering bone remodeling to mitigate stress shielding effect
Copyright © 2024. Published by Elsevier Ltd..
The embracing fixator is one of the widely used internal fixation implants for bone fracture treatment. However, the stress shielding effect, a stress imbalance between the implant and bone caused by the mismatch in mechanical properties between them, is a significant and critical issue that may lead to treatment failure. Thus, it is of great importance to design the implant with an appropriate stiffness which can mitigate the stress shielding effect and provide the most favorable mechanical environment for bone healing and remodeling. To this end, a time-dependent topology optimization algorithm considering bone remodeling is proposed to optimize an embracing fixator used in the tibia fracture treatment. The change of callus density over time is simulated based on a bone remodeling model, and the callus density after a period of bone remodeling is selected to be the design objective to maximize. The design constraints include volume and the compliance of the whole fixation system. Meanwhile, the influence of the constraints on the regularity of material distribution of the optimized result is also studied. Besides, to test the effectiveness of the consideration of the bone remodeling in the embracing fixator design, a topology optimization concerning the minimization of the compliance of the entire system is also performed to make a comparison. Finally, the safety performance of optimized results considering bone remodeling is also verified by static analysis.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2024 |
|---|---|
| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:125 |
|---|---|
| Enthalten in: |
Medical engineering & physics - 125(2024) vom: 18. März, Seite 104122 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Xiong, Wanyue [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Bone remodeling |
|---|
| Anmerkungen: |
Date Completed 22.03.2024 Date Revised 02.04.2024 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1016/j.medengphy.2024.104122 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM369983777 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM369983777 | ||
| 003 | DE-627 | ||
| 005 | 20240403000550.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 240322s2024 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.medengphy.2024.104122 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1361.xml |
| 035 | |a (DE-627)NLM369983777 | ||
| 035 | |a (NLM)38508793 | ||
| 035 | |a (PII)S1350-4533(24)00023-7 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Xiong, Wanyue |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Topology optimization of embracing fixator considering bone remodeling to mitigate stress shielding effect |
| 264 | 1 | |c 2024 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 22.03.2024 | ||
| 500 | |a Date Revised 02.04.2024 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2024. Published by Elsevier Ltd. | ||
| 520 | |a The embracing fixator is one of the widely used internal fixation implants for bone fracture treatment. However, the stress shielding effect, a stress imbalance between the implant and bone caused by the mismatch in mechanical properties between them, is a significant and critical issue that may lead to treatment failure. Thus, it is of great importance to design the implant with an appropriate stiffness which can mitigate the stress shielding effect and provide the most favorable mechanical environment for bone healing and remodeling. To this end, a time-dependent topology optimization algorithm considering bone remodeling is proposed to optimize an embracing fixator used in the tibia fracture treatment. The change of callus density over time is simulated based on a bone remodeling model, and the callus density after a period of bone remodeling is selected to be the design objective to maximize. The design constraints include volume and the compliance of the whole fixation system. Meanwhile, the influence of the constraints on the regularity of material distribution of the optimized result is also studied. Besides, to test the effectiveness of the consideration of the bone remodeling in the embracing fixator design, a topology optimization concerning the minimization of the compliance of the entire system is also performed to make a comparison. Finally, the safety performance of optimized results considering bone remodeling is also verified by static analysis | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 4 | |a Bone remodeling | |
| 650 | 4 | |a Embracing fixator | |
| 650 | 4 | |a Stress shielding | |
| 650 | 4 | |a Topology optimization | |
| 700 | 1 | |a Ding, Xiaohong |e verfasserin |4 aut | |
| 700 | 1 | |a Zhang, Heng |e verfasserin |4 aut | |
| 700 | 1 | |a Hu, Tiannan |e verfasserin |4 aut | |
| 700 | 1 | |a Xu, Shipeng |e verfasserin |4 aut | |
| 700 | 1 | |a Duan, Pengyun |e verfasserin |4 aut | |
| 700 | 1 | |a Huang, Baixuan |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Medical engineering & physics |d 1997 |g 125(2024) vom: 18. März, Seite 104122 |w (DE-627)NLM074657348 |x 1873-4030 |7 nnns |
| 773 | 1 | 8 | |g volume:125 |g year:2024 |g day:18 |g month:03 |g pages:104122 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1016/j.medengphy.2024.104122 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 125 |j 2024 |b 18 |c 03 |h 104122 | ||