Prognosis of Bilateral Sudden Sensorineural Hearing Loss : A Systematic Review and Meta-Analysis
© 2024 The American Laryngological, Rhinological and Otological Society, Inc..
OBJECTIVES: To comprehensively examine the characteristics and prognosis of bilateral sudden sensorineural hearing loss (BSSHL) and its subtypes compared to unilateral sudden sensorineural hearing loss (USSHL).
DATA SOURCES: PubMed, Scopus, and CINAHL.
REVIEW METHODS: Databases were searched from inception to December 5, 2023, for studies reporting patient characteristics and audiometric outcomes for BSSHL and its simultaneous (Si-BSSHL) and sequential (Se-BSSHL) subtypes. Meta-analysis of continuous measures, proportions (%), mean differences (Δ), and odds ratio (OR) were performed.
RESULTS: Eleven studies were included, consisting of 368 patients with BSSHL and 2,705 patients with USSHL. The pooled prevalence among all SSHL cases was 88.1% (95% CI: 81.2%-93.6%) for USSHL and 11.9% (95% CI: 6.4% to 18.8%) for BSSHL. PTA improvement following treatment with steroids was significantly worse in patients with BSSHL (Δ15.3 dB; 95% CI: 14.6 to 15.9; p < 0.0001) compared to patients with USSHL. There was no significant difference in post-treatment PTA improvement between the BSSHL subtypes. Patients with Si-BSSHL were significantly less likely to have an idiopathic etiology (OR: 0.4; 95% CI: 0.2 to 0.8; p = 0.01) and significantly more likely to have an autoimmune disease etiology (OR: 27.4; 95% CI: 2.2 to 336.1; p = 0.01), comorbid cardiovascular disease (OR: 2.3; 95% CI: 1.1 to 5.1; p = 0.03), and comorbid hypertension (OR: 2.5; 95% CI: 1.6 to 3.8; p < 0.0001) compared to patients with USSHL.
CONCLUSIONS: BSSHL is a considerably rarer form of SSHL with worse prognosis compared to USSHL. BSSHL, and Si-BSSHL in particular, has significantly greater associations with systemic pathologies compared to USSHL. Laryngoscope, 2024.
Medienart: |
E-Artikel |
---|
Erscheinungsjahr: |
2024 |
---|---|
Erschienen: |
2024 |
Enthalten in: |
Zur Gesamtaufnahme - year:2024 |
---|---|
Enthalten in: |
The Laryngoscope - (2024) vom: 20. März |
Sprache: |
Englisch |
---|
Beteiligte Personen: |
Bhat, Akash M [VerfasserIn] |
---|
Links: |
---|
Themen: |
Bilateral |
---|
Anmerkungen: |
Date Revised 20.03.2024 published: Print-Electronic Citation Status Publisher |
---|
doi: |
10.1002/lary.31404 |
---|
funding: |
|
---|---|
Förderinstitution / Projekttitel: |
|
PPN (Katalog-ID): |
NLM369960505 |
---|
LEADER | 01000naa a22002652 4500 | ||
---|---|---|---|
001 | NLM369960505 | ||
003 | DE-627 | ||
005 | 20240320235646.0 | ||
007 | cr uuu---uuuuu | ||
008 | 240320s2024 xx |||||o 00| ||eng c | ||
024 | 7 | |a 10.1002/lary.31404 |2 doi | |
028 | 5 | 2 | |a pubmed24n1337.xml |
035 | |a (DE-627)NLM369960505 | ||
035 | |a (NLM)38506449 | ||
040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
041 | |a eng | ||
100 | 1 | |a Bhat, Akash M |e verfasserin |4 aut | |
245 | 1 | 0 | |a Prognosis of Bilateral Sudden Sensorineural Hearing Loss |b A Systematic Review and Meta-Analysis |
264 | 1 | |c 2024 | |
336 | |a Text |b txt |2 rdacontent | ||
337 | |a ƒaComputermedien |b c |2 rdamedia | ||
338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
500 | |a Date Revised 20.03.2024 | ||
500 | |a published: Print-Electronic | ||
500 | |a Citation Status Publisher | ||
520 | |a © 2024 The American Laryngological, Rhinological and Otological Society, Inc. | ||
520 | |a OBJECTIVES: To comprehensively examine the characteristics and prognosis of bilateral sudden sensorineural hearing loss (BSSHL) and its subtypes compared to unilateral sudden sensorineural hearing loss (USSHL) | ||
520 | |a DATA SOURCES: PubMed, Scopus, and CINAHL | ||
520 | |a REVIEW METHODS: Databases were searched from inception to December 5, 2023, for studies reporting patient characteristics and audiometric outcomes for BSSHL and its simultaneous (Si-BSSHL) and sequential (Se-BSSHL) subtypes. Meta-analysis of continuous measures, proportions (%), mean differences (Δ), and odds ratio (OR) were performed | ||
520 | |a RESULTS: Eleven studies were included, consisting of 368 patients with BSSHL and 2,705 patients with USSHL. The pooled prevalence among all SSHL cases was 88.1% (95% CI: 81.2%-93.6%) for USSHL and 11.9% (95% CI: 6.4% to 18.8%) for BSSHL. PTA improvement following treatment with steroids was significantly worse in patients with BSSHL (Δ15.3 dB; 95% CI: 14.6 to 15.9; p < 0.0001) compared to patients with USSHL. There was no significant difference in post-treatment PTA improvement between the BSSHL subtypes. Patients with Si-BSSHL were significantly less likely to have an idiopathic etiology (OR: 0.4; 95% CI: 0.2 to 0.8; p = 0.01) and significantly more likely to have an autoimmune disease etiology (OR: 27.4; 95% CI: 2.2 to 336.1; p = 0.01), comorbid cardiovascular disease (OR: 2.3; 95% CI: 1.1 to 5.1; p = 0.03), and comorbid hypertension (OR: 2.5; 95% CI: 1.6 to 3.8; p < 0.0001) compared to patients with USSHL | ||
520 | |a CONCLUSIONS: BSSHL is a considerably rarer form of SSHL with worse prognosis compared to USSHL. BSSHL, and Si-BSSHL in particular, has significantly greater associations with systemic pathologies compared to USSHL. Laryngoscope, 2024 | ||
650 | 4 | |a Journal Article | |
650 | 4 | |a Review | |
650 | 4 | |a bilateral | |
650 | 4 | |a sequential | |
650 | 4 | |a simultaneous | |
650 | 4 | |a sudden sensorineural hearing loss | |
700 | 1 | |a Nanu, Douglas P |e verfasserin |4 aut | |
700 | 1 | |a Nguyen, Shaun A |e verfasserin |4 aut | |
700 | 1 | |a Meyer, Ted A |e verfasserin |4 aut | |
700 | 1 | |a Labadie, Robert F |e verfasserin |4 aut | |
773 | 0 | 8 | |i Enthalten in |t The Laryngoscope |d 1945 |g (2024) vom: 20. März |w (DE-627)NLM000205370 |x 1531-4995 |7 nnns |
773 | 1 | 8 | |g year:2024 |g day:20 |g month:03 |
856 | 4 | 0 | |u http://dx.doi.org/10.1002/lary.31404 |3 Volltext |
912 | |a GBV_USEFLAG_A | ||
912 | |a GBV_NLM | ||
951 | |a AR | ||
952 | |j 2024 |b 20 |c 03 |