Effects of case volume on short- and long-term outcomes following cadaveric lung transplantation in Japan
2024 Journal of Thoracic Disease. All rights reserved..
Background: Despite the low number of lung transplantations (LTs) in Japan, 10 LT facilities are accredited and good outcomes have been reported. A database review was conducted to clarify the impact of case volume at LT facilities in Japan on short- and long-term outcomes.
Methods: All cadaveric LT cases treated between 2000 and 2021 in Japan were analyzed using the database of the Japanese Society of Lung and Heart-Lung Transplantation (JSLHT). The nine institutions represented were categorized into the low-volume (LV; <80 cumulative LT cases, <8 LTs/year, n=5) and high-volume (HV; ≥80 cumulative LT cases, ≥8 LTs/year, n=4) centers. Ninety-day and 1-year mortality, as well as 5- and 10-year survival data were evaluated.
Results: A total of 658 cadaveric LTs were performed at the nine institutions. The 90-day rates of mortality at the HV and LV centers were 3.5% and 3.9%, respectively (P=0.801), while the 1-year mortality rates were 9.2% and 11.5%, respectively (P=0.199). Additionally, log-rank analysis of Kaplan-Meier curves showing case volume did not reveal a significant difference in long-term survival between the HV and LV centers (P=0.272), though the LV centers had wide differences for long-term outcomes (P=0.030).
Conclusions: Case volume did not have effects on short- or long-term outcomes following LT in Japan, while there were large variations in long-term outcomes among the LV centers compared to those of the HV centers.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2024 |
|---|---|
| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:16 |
|---|---|
| Enthalten in: |
Journal of thoracic disease - 16(2024), 2 vom: 29. Feb., Seite 1473-1479 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Chida, Masayuki [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Case volume |
|---|
| Anmerkungen: |
Date Revised 21.03.2024 published: Print-Electronic Citation Status PubMed-not-MEDLINE |
|---|
| doi: |
10.21037/jtd-23-90 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM369946901 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM369946901 | ||
| 003 | DE-627 | ||
| 005 | 20240322000954.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 240320s2024 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.21037/jtd-23-90 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1339.xml |
| 035 | |a (DE-627)NLM369946901 | ||
| 035 | |a (NLM)38505082 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Chida, Masayuki |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Effects of case volume on short- and long-term outcomes following cadaveric lung transplantation in Japan |
| 264 | 1 | |c 2024 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Revised 21.03.2024 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a 2024 Journal of Thoracic Disease. All rights reserved. | ||
| 520 | |a Background: Despite the low number of lung transplantations (LTs) in Japan, 10 LT facilities are accredited and good outcomes have been reported. A database review was conducted to clarify the impact of case volume at LT facilities in Japan on short- and long-term outcomes | ||
| 520 | |a Methods: All cadaveric LT cases treated between 2000 and 2021 in Japan were analyzed using the database of the Japanese Society of Lung and Heart-Lung Transplantation (JSLHT). The nine institutions represented were categorized into the low-volume (LV; <80 cumulative LT cases, <8 LTs/year, n=5) and high-volume (HV; ≥80 cumulative LT cases, ≥8 LTs/year, n=4) centers. Ninety-day and 1-year mortality, as well as 5- and 10-year survival data were evaluated | ||
| 520 | |a Results: A total of 658 cadaveric LTs were performed at the nine institutions. The 90-day rates of mortality at the HV and LV centers were 3.5% and 3.9%, respectively (P=0.801), while the 1-year mortality rates were 9.2% and 11.5%, respectively (P=0.199). Additionally, log-rank analysis of Kaplan-Meier curves showing case volume did not reveal a significant difference in long-term survival between the HV and LV centers (P=0.272), though the LV centers had wide differences for long-term outcomes (P=0.030) | ||
| 520 | |a Conclusions: Case volume did not have effects on short- or long-term outcomes following LT in Japan, while there were large variations in long-term outcomes among the LV centers compared to those of the HV centers | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Lung transplantation (LT) | |
| 650 | 4 | |a case volume | |
| 650 | 4 | |a long-term survival | |
| 650 | 4 | |a mortality | |
| 700 | 1 | |a Inoue, Takashi |e verfasserin |4 aut | |
| 700 | 1 | |a Nakajima, Takahiro |e verfasserin |4 aut | |
| 700 | 1 | |a Okada, Yoshinori |e verfasserin |4 aut | |
| 700 | 1 | |a Oishi, Hisashi |e verfasserin |4 aut | |
| 700 | 1 | |a Nakajima, Jun |e verfasserin |4 aut | |
| 700 | 1 | |a Sato, Masaaki |e verfasserin |4 aut | |
| 700 | 1 | |a Yoshino, Ichiro |e verfasserin |4 aut | |
| 700 | 1 | |a Suzuki, Hidemi |e verfasserin |4 aut | |
| 700 | 1 | |a Nakajima, Daisuke |e verfasserin |4 aut | |
| 700 | 1 | |a Shintani, Yasushi |e verfasserin |4 aut | |
| 700 | 1 | |a Kanou, Takashi |e verfasserin |4 aut | |
| 700 | 1 | |a Toyooka, Shinichi |e verfasserin |4 aut | |
| 700 | 1 | |a Miyoshi, Kentaroh |e verfasserin |4 aut | |
| 700 | 1 | |a Shiraishi, Takeshi |e verfasserin |4 aut | |
| 700 | 1 | |a Sato, Toshihiko |e verfasserin |4 aut | |
| 700 | 1 | |a Matsumoto, Keitaro |e verfasserin |4 aut | |
| 700 | 1 | |a Nagayasu, Takeshi |e verfasserin |4 aut | |
| 700 | 1 | |a Hoshikawa, Yasushi |e verfasserin |4 aut | |
| 700 | 1 | |a Matsuda, Yasushi |e verfasserin |4 aut | |
| 700 | 1 | |a Maeda, Sumiko |e verfasserin |4 aut | |
| 700 | 1 | |a Date, Hiroshi |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Journal of thoracic disease |d 2010 |g 16(2024), 2 vom: 29. Feb., Seite 1473-1479 |w (DE-627)NLM219116938 |x 2072-1439 |7 nnns |
| 773 | 1 | 8 | |g volume:16 |g year:2024 |g number:2 |g day:29 |g month:02 |g pages:1473-1479 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.21037/jtd-23-90 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 16 |j 2024 |e 2 |b 29 |c 02 |h 1473-1479 | ||