Artificial intelligence (AI)-assisted chest computer tomography (CT) insights : a study on intensive care unit (ICU) admittance trends in 78 coronavirus disease 2019 (COVID-19) patients
2024 Journal of Thoracic Disease. All rights reserved..
Background: The global coronavirus disease 2019 (COVID-19) pandemic has posed substantial challenges for healthcare systems, notably the increased demand for chest computed tomography (CT) scans, which lack automated analysis. Our study addresses this by utilizing artificial intelligence-supported automated computer analysis to investigate lung involvement distribution and extent in COVID-19 patients. Additionally, we explore the association between lung involvement and intensive care unit (ICU) admission, while also comparing computer analysis performance with expert radiologists' assessments.
Methods: A total of 81 patients from an open-source COVID database with confirmed COVID-19 infection were included in the study. Three patients were excluded. Lung involvement was assessed in 78 patients using CT scans, and the extent of infiltration and collapse was quantified across various lung lobes and regions. The associations between lung involvement and ICU admission were analysed. Additionally, the computer analysis of COVID-19 involvement was compared against a human rating provided by radiological experts.
Results: The results showed a higher degree of infiltration and collapse in the lower lobes compared to the upper lobes (P<0.05). No significant difference was detected in the COVID-19-related involvement of the left and right lower lobes. The right middle lobe demonstrated lower involvement compared to the right lower lobes (P<0.05). When examining the regions, significantly more COVID-19 involvement was found when comparing the posterior vs. the anterior halves and the lower vs. the upper half of the lungs. Patients, who required ICU admission during their treatment exhibited significantly higher COVID-19 involvement in their lung parenchyma according to computer analysis, compared to patients who remained in general wards. Patients with more than 40% COVID-19 involvement were almost exclusively treated in intensive care. A high correlation was observed between computer detection of COVID-19 affections and the rating by radiological experts.
Conclusions: The findings suggest that the extent of lung involvement, particularly in the lower lobes, dorsal lungs, and lower half of the lungs, may be associated with the need for ICU admission in patients with COVID-19. Computer analysis showed a high correlation with expert rating, highlighting its potential utility in clinical settings for assessing lung involvement. This information may help guide clinical decision-making and resource allocation during ongoing or future pandemics. Further studies with larger sample sizes are warranted to validate these findings.
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| Medienart: |
E-Artikel |
| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:16 |
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| Enthalten in: |
Journal of thoracic disease - 16(2024), 2 vom: 29. Feb., Seite 1009-1020 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Bumm, Rudolf [VerfasserIn] |
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| Anmerkungen: |
Date Revised 29.03.2024 published: Print-Electronic UpdateOf: Res Sq. 2023 Jul 05;:. - PMID 37333197 Citation Status PubMed-not-MEDLINE |
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| doi: |
10.21037/jtd-23-1150 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM369946170 |
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| 245 | 1 | 0 | |a Artificial intelligence (AI)-assisted chest computer tomography (CT) insights |b a study on intensive care unit (ICU) admittance trends in 78 coronavirus disease 2019 (COVID-19) patients |
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| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a 2024 Journal of Thoracic Disease. All rights reserved. | ||
| 520 | |a Background: The global coronavirus disease 2019 (COVID-19) pandemic has posed substantial challenges for healthcare systems, notably the increased demand for chest computed tomography (CT) scans, which lack automated analysis. Our study addresses this by utilizing artificial intelligence-supported automated computer analysis to investigate lung involvement distribution and extent in COVID-19 patients. Additionally, we explore the association between lung involvement and intensive care unit (ICU) admission, while also comparing computer analysis performance with expert radiologists' assessments | ||
| 520 | |a Methods: A total of 81 patients from an open-source COVID database with confirmed COVID-19 infection were included in the study. Three patients were excluded. Lung involvement was assessed in 78 patients using CT scans, and the extent of infiltration and collapse was quantified across various lung lobes and regions. The associations between lung involvement and ICU admission were analysed. Additionally, the computer analysis of COVID-19 involvement was compared against a human rating provided by radiological experts | ||
| 520 | |a Results: The results showed a higher degree of infiltration and collapse in the lower lobes compared to the upper lobes (P<0.05). No significant difference was detected in the COVID-19-related involvement of the left and right lower lobes. The right middle lobe demonstrated lower involvement compared to the right lower lobes (P<0.05). When examining the regions, significantly more COVID-19 involvement was found when comparing the posterior vs. the anterior halves and the lower vs. the upper half of the lungs. Patients, who required ICU admission during their treatment exhibited significantly higher COVID-19 involvement in their lung parenchyma according to computer analysis, compared to patients who remained in general wards. Patients with more than 40% COVID-19 involvement were almost exclusively treated in intensive care. A high correlation was observed between computer detection of COVID-19 affections and the rating by radiological experts | ||
| 520 | |a Conclusions: The findings suggest that the extent of lung involvement, particularly in the lower lobes, dorsal lungs, and lower half of the lungs, may be associated with the need for ICU admission in patients with COVID-19. Computer analysis showed a high correlation with expert rating, highlighting its potential utility in clinical settings for assessing lung involvement. This information may help guide clinical decision-making and resource allocation during ongoing or future pandemics. Further studies with larger sample sizes are warranted to validate these findings | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a COVID lung involvement | |
| 650 | 4 | |a Coronavirus disease 2019 (COVID-19) | |
| 650 | 4 | |a artificial intelligence-supported computed tomography computer analysis (AI-supported CT computer analysis) | |
| 650 | 4 | |a clinical decision-making | |
| 650 | 4 | |a forecast of intensive care unit admission (forecast of ICU admission) | |
| 700 | 1 | |a Zaffino, Paolo |e verfasserin |4 aut | |
| 700 | 1 | |a Lasso, Andras |e verfasserin |4 aut | |
| 700 | 1 | |a Estépar, Raúl San José |e verfasserin |4 aut | |
| 700 | 1 | |a Pieper, Steven |e verfasserin |4 aut | |
| 700 | 1 | |a Wasserthal, Jakob |e verfasserin |4 aut | |
| 700 | 1 | |a Spadea, Maria Francesca |e verfasserin |4 aut | |
| 700 | 1 | |a Latshang, Tsogyal |e verfasserin |4 aut | |
| 700 | 1 | |a Kawel-Boehm, Nadine |e verfasserin |4 aut | |
| 700 | 1 | |a Wäckerlin, Adrian |e verfasserin |4 aut | |
| 700 | 1 | |a Werner, Raphael |e verfasserin |4 aut | |
| 700 | 1 | |a Hässig, Gabriela |e verfasserin |4 aut | |
| 700 | 1 | |a Furrer, Markus |e verfasserin |4 aut | |
| 700 | 1 | |a Kikinis, Ron |e verfasserin |4 aut | |
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