Association between dietary calcium to Phosphorus Ratio and the odds of ulcerative colitis : A case-control study
© 2024 The Authors. Published by Elsevier Ltd..
Background & aims: Ulcerative colitis (UC) is a recurrent, inflammatory, autoimmune intestinal disease. The dietary calcium to phosphorus (Ca:P) ratio is suggested to affect the inividuals' normal metabolic and inflammatory pathways. The present study aimed to investigate the association between dietary Ca:P ratio and the odds of developing UC in a case-control format.
Methods: The study included sixty-two currently diagnosed UC patients and one hundred twenty-four matched controls, designed as a case-control study. The dietary intakes of the participants were assessed by a food frequency questionnaire (FFQ), and the dietary Ca:P ratio was calculated. The association between tertiles of Ca:P ratio and UC was examined using the logistic regression. P-values <0.05 were considered as significant.
Results: The study sample consisted of participants with an average age of 36.63 ± 12.42 years and a mean body mass index (BMI) of 25.39 ± 3.82 kg/m2. The overall energy-adjusted ratio of Ca:P was 0.74 ± 0.11. In the multivariate model, after adjustment for potential confounders, participants in the third tertile of dietary Ca:P ratio had a lower odds of developing UC compared to the lowest tertlie (OR: 0.34, 95% CI: 0.13-0.87; p = 0.026).
Conclusion: Our results indicate that a higher ratio of dietary Ca:P ratio might be protective against developing UC. However, further studies are warranted to examine this association in various populations.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:10 |
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| Enthalten in: |
Heliyon - 10(2024), 6 vom: 30. März, Seite e27556 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Tangestani, Hadith [VerfasserIn] |
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| Links: |
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| Themen: |
Dietary calcium |
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| Anmerkungen: |
Date Revised 20.03.2024 published: Electronic-eCollection Citation Status PubMed-not-MEDLINE |
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| doi: |
10.1016/j.heliyon.2024.e27556 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM369906330 |
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| 520 | |a © 2024 The Authors. Published by Elsevier Ltd. | ||
| 520 | |a Background & aims: Ulcerative colitis (UC) is a recurrent, inflammatory, autoimmune intestinal disease. The dietary calcium to phosphorus (Ca:P) ratio is suggested to affect the inividuals' normal metabolic and inflammatory pathways. The present study aimed to investigate the association between dietary Ca:P ratio and the odds of developing UC in a case-control format | ||
| 520 | |a Methods: The study included sixty-two currently diagnosed UC patients and one hundred twenty-four matched controls, designed as a case-control study. The dietary intakes of the participants were assessed by a food frequency questionnaire (FFQ), and the dietary Ca:P ratio was calculated. The association between tertiles of Ca:P ratio and UC was examined using the logistic regression. P-values <0.05 were considered as significant | ||
| 520 | |a Results: The study sample consisted of participants with an average age of 36.63 ± 12.42 years and a mean body mass index (BMI) of 25.39 ± 3.82 kg/m2. The overall energy-adjusted ratio of Ca:P was 0.74 ± 0.11. In the multivariate model, after adjustment for potential confounders, participants in the third tertile of dietary Ca:P ratio had a lower odds of developing UC compared to the lowest tertlie (OR: 0.34, 95% CI: 0.13-0.87; p = 0.026) | ||
| 520 | |a Conclusion: Our results indicate that a higher ratio of dietary Ca:P ratio might be protective against developing UC. However, further studies are warranted to examine this association in various populations | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Dietary calcium | |
| 650 | 4 | |a Dietary intake | |
| 650 | 4 | |a Dietary phosphorus | |
| 650 | 4 | |a Inflammatory bowel diseases | |
| 650 | 4 | |a Ulcerative colitis | |
| 700 | 1 | |a Jamshidi, Ali |e verfasserin |4 aut | |
| 700 | 1 | |a Yari, Zahra |e verfasserin |4 aut | |
| 700 | 1 | |a Jalaliyan, Zahrasadat |e verfasserin |4 aut | |
| 700 | 1 | |a Ghalandari, Hamid |e verfasserin |4 aut | |
| 700 | 1 | |a Hekmatdoost, Azita |e verfasserin |4 aut | |
| 700 | 1 | |a Rashvand, Samaneh |e verfasserin |4 aut | |
| 700 | 1 | |a Mohammadi Baghmolae, Amirhossein |e verfasserin |4 aut | |
| 700 | 1 | |a Emamat, Hadi |e verfasserin |4 aut | |
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