Use of Chitosan as a Precursor for Multiple Applications in Medicinal Chemistry : Recent Significant Contributions

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Chitosan (CS) is a polymer made up of mainly deacetylated β-1,4 D-glucosamine units, which is part of a large group of D-glucosamine oligomers known as chitooligosaccharides, which can be obtained from chitin, most abundant natural polymer after cellulose and central component of the shrimp exoskeleton. It is known that it can be used for the development of materials, among which its use stands out in wastewater treatment (removal of metal ions, dyes, and as a membrane in purification processes), food industry (anti-cholesterol and fat, packaging material, preservative, and food additive), agriculture (seed and fertilizer coating, controlled release agrochemicals), pulp and paper industry (surface treatment, adhesive paper), cosmetics (body creams, lotions, etc.), in the engineering of tissues, wound healing, as excipients for drug administration, gels, membranes, nanofibers, beads, microparticles, nanoparticles, scaffolds, sponges, and diverse biological ones, specifically antibacterial and antifungal activities. This article reviews the main contributions published in the last ten years regarding the use and application of CS in medical chemistry. The applications exposed here involve regenerative medicine in the design of bioprocesses and tissue engineering, Pharmaceutical sciences to obtain biomaterials, polymers, biomedicine, and the use of nanomaterials and nanotechnology, toxicology, and Clinical Pharmaceuticals, emphasizing the perspectives and the direction that can take research in this area.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - year:2024

Enthalten in:

Mini reviews in medicinal chemistry - (2024) vom: 18. März

Sprache:

Englisch

Beteiligte Personen:

Quiroga, Diego [VerfasserIn]
Coy-Barrera, Carlos [VerfasserIn]

Links:

Volltext

Themen:

Biological activity.
Biopolymers
Chitosan
Journal Article
Medical applications
Nanofibers
Novel materials

Anmerkungen:

Date Revised 19.03.2024

published: Print-Electronic

Citation Status Publisher

doi:

10.2174/0113895575275799240306105615

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM369899369