A novel therapy for intractable chronic cough

© 2024 The Authors. Respirology Case Reports published by John Wiley & Sons Australia, Ltd on behalf of The Asian Pacific Society of Respirology..

Two cases of intractable chronic cough improved significantly with humidified high flow therapy (HHFT). A 59-year-old woman with Primary Sjogren's disease and interstitial lung disease, was trialled on a Fisher and Paykel myAIRVO™ system. She reported sustained benefits of uninterrupted sleep and increased socialization with tapering use of HHFT. A 67-year-old woman with idiopathic pulmonary fibrosis also benefited from the use of myAIRVO™. She had relentless cough with minimal movement, and nocturnal cough causing fragmented sleep. Her cough subsided considerably with continuous HHFT, but recurred without. Both patients reported significant reductions in the cough visual analogue scale. The mechanisms by which HHFT improve intractable cough may include reducing airway dryness, inhibition of neutrophil inflammation and mucus obstruction, and splinting of the airways. HHFT significantly improved cough and health-related quality of life in two patients with interstitial lung disease. Further research is warranted to explore the role of domiciliary HHFT.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:12

Enthalten in:

Respirology case reports - 12(2024), 3 vom: 14. März, Seite e01323

Sprache:

Englisch

Beteiligte Personen:

Bricknell, Matthew [VerfasserIn]
Zhao, Chris Zi-Fan [VerfasserIn]
Smallwood, Natasha [VerfasserIn]
Goh, Nicole [VerfasserIn]

Links:

Volltext

Themen:

Case Reports
Chronic cough
Humidified high flow therapy
Intractable cough

Anmerkungen:

Date Revised 19.03.2024

published: Electronic-eCollection

Citation Status PubMed-not-MEDLINE

doi:

10.1002/rcr2.1323

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM369859871