Study of erythrocyte sedimentation in human blood through the photoacoustic signals analysis

© 2024 The Authors..

Introduction: In this study, we utilized the pulsed photoacoustic (PA) technique to analyze globular sedimentation in whole human blood, with a focus on distinguishing between healthy individuals and those with hemolytic anemia.

Methods: Blood samples were collected from both healthy individuals (women and men) and those with hemolytic anemia, and temporal and spectral parameters of PA signals were employed for analysis.

Results: Significant differences (p < 0.05) were observed in PA metrics between the two groups. The proposed spectral analysis allowed significant differentiation within a 25-minute measurement window. Anemic blood samples exhibited higher erythrocyte sedimentation rate (ESR) values, indicating increased erythrocyte aggregation.

Discussion: This study underscores the potential of PA signal analysis in ESR assessment as an efficient method for distinguishing between healthy and anemic blood, surpassing traditional approaches. It represents a promising contribution to the development of precise and sensitive techniques for analyzing human blood samples in clinical settings.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:37

Enthalten in:

Photoacoustics - 37(2024) vom: 15. März, Seite 100599

Sprache:

Englisch

Beteiligte Personen:

Pérez-Pacheco, Argelia [VerfasserIn]
Ramírez-Chavarría, Roberto G [VerfasserIn]
Colín-García, Marco Polo [VerfasserIn]
Cortés-Ortegón, Flor Del Carmen [VerfasserIn]
Quispe-Siccha, Rosa María [VerfasserIn]
Martínez-Tovar, Adolfo [VerfasserIn]
Olarte-Carrillo, Irma [VerfasserIn]
Polo-Parada, Luis [VerfasserIn]
Gutiérrez-Juárez, Gerardo [VerfasserIn]

Links:

Volltext

Themen:

Aggregation
Anemia
Erythrocyte sedimentation
Journal Article
Pulsed photoacoustic
Speed of sound
Whole human blood

Anmerkungen:

Date Revised 19.03.2024

published: Electronic-eCollection

Citation Status PubMed-not-MEDLINE

doi:

10.1016/j.pacs.2024.100599

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM369856406