Psychological burden associated with incident persistent symptoms and their evolution during the COVID-19 pandemic : a prospective population-based study
© Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. Published by BMJ..
BACKGROUND: Identifying factors that predict the course of persistent symptoms that occurred during the COVID-19 pandemic is a public health issue. Modifiable factors could be targeted in therapeutic interventions.
OBJECTIVE: This prospective study based on the population-based CONSTANCES cohort examined whether the psychological burden associated with incident persistent symptoms (ie, that first occurred from March 2020) would predict having ≥1 persistent symptom 6-10 months later.
METHODS: A total of 8424 participants (mean age=54.6 years (SD=12.6), 57.2% women) having ≥1 incident persistent symptom at baseline (ie, between December 2020 and February 2021) were included. The psychological burden associated with these persistent symptoms was assessed with the Somatic Symptom Disorder-B Criteria Scale (SSD-12). The outcome was having ≥1 persistent symptom at follow-up. Adjusted binary logistic regression models examined the association between the SSD-12 score and the outcome.
FINDINGS: At follow-up, 1124 participants (13.3%) still had ≥1 persistent symptom. The SSD-12 score at baseline was associated with persistent symptoms at follow-up in both participants with (OR (95% CI) for one IQR increase: 1.42 (1.09 to 1.84)) and without SARS-CoV-2 infection prior to baseline (1.39 (1.25 to 1.55)). Female gender, older age, poorer self-rated health and infection prior to baseline were also associated with persistent symptoms at follow-up.
CONCLUSIONS: The psychological burden associated with persistent symptoms at baseline predicted the presence of ≥1 persistent symptom at follow-up regardless of infection prior to baseline.
CLINICAL IMPLICATIONS: Intervention studies should test whether reducing the psychological burden associated with persistent symptoms could improve the course of these symptoms.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2024 |
|---|---|
| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:27 |
|---|---|
| Enthalten in: |
BMJ mental health - 27(2024), 1 vom: 15. März |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Pignon, Baptiste [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
|---|
| Anmerkungen: |
Date Completed 18.03.2024 Date Revised 25.04.2024 published: Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1136/bmjment-2023-300907 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM369803671 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM369803671 | ||
| 003 | DE-627 | ||
| 005 | 20240425233158.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 240316s2024 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1136/bmjment-2023-300907 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1386.xml |
| 035 | |a (DE-627)NLM369803671 | ||
| 035 | |a (NLM)38490690 | ||
| 035 | |a (PII)e300907 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Pignon, Baptiste |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Psychological burden associated with incident persistent symptoms and their evolution during the COVID-19 pandemic |b a prospective population-based study |
| 264 | 1 | |c 2024 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 18.03.2024 | ||
| 500 | |a Date Revised 25.04.2024 | ||
| 500 | |a published: Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. Published by BMJ. | ||
| 520 | |a BACKGROUND: Identifying factors that predict the course of persistent symptoms that occurred during the COVID-19 pandemic is a public health issue. Modifiable factors could be targeted in therapeutic interventions | ||
| 520 | |a OBJECTIVE: This prospective study based on the population-based CONSTANCES cohort examined whether the psychological burden associated with incident persistent symptoms (ie, that first occurred from March 2020) would predict having ≥1 persistent symptom 6-10 months later | ||
| 520 | |a METHODS: A total of 8424 participants (mean age=54.6 years (SD=12.6), 57.2% women) having ≥1 incident persistent symptom at baseline (ie, between December 2020 and February 2021) were included. The psychological burden associated with these persistent symptoms was assessed with the Somatic Symptom Disorder-B Criteria Scale (SSD-12). The outcome was having ≥1 persistent symptom at follow-up. Adjusted binary logistic regression models examined the association between the SSD-12 score and the outcome | ||
| 520 | |a FINDINGS: At follow-up, 1124 participants (13.3%) still had ≥1 persistent symptom. The SSD-12 score at baseline was associated with persistent symptoms at follow-up in both participants with (OR (95% CI) for one IQR increase: 1.42 (1.09 to 1.84)) and without SARS-CoV-2 infection prior to baseline (1.39 (1.25 to 1.55)). Female gender, older age, poorer self-rated health and infection prior to baseline were also associated with persistent symptoms at follow-up | ||
| 520 | |a CONCLUSIONS: The psychological burden associated with persistent symptoms at baseline predicted the presence of ≥1 persistent symptom at follow-up regardless of infection prior to baseline | ||
| 520 | |a CLINICAL IMPLICATIONS: Intervention studies should test whether reducing the psychological burden associated with persistent symptoms could improve the course of these symptoms | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a COVID-19 | |
| 700 | 1 | |a Matta, Joane |e verfasserin |4 aut | |
| 700 | 1 | |a Wiernik, Emmanuel |e verfasserin |4 aut | |
| 700 | 1 | |a Toussaint, Anne |e verfasserin |4 aut | |
| 700 | 1 | |a Loewe, Bernd |e verfasserin |4 aut | |
| 700 | 1 | |a Robineau, Olivier |e verfasserin |4 aut | |
| 700 | 1 | |a Carrat, Fabrice |e verfasserin |4 aut | |
| 700 | 1 | |a Severi, Gianluca |e verfasserin |4 aut | |
| 700 | 1 | |a Touvier, Mathilde |e verfasserin |4 aut | |
| 700 | 1 | |a Gouraud, Clement |e verfasserin |4 aut | |
| 700 | 1 | |a Ouazana Vedrines, Charles |e verfasserin |4 aut | |
| 700 | 1 | |a Pitron, Victor |e verfasserin |4 aut | |
| 700 | 1 | |a Ranque, Brigitte |e verfasserin |4 aut | |
| 700 | 1 | |a Hoertel, Nicolas |e verfasserin |4 aut | |
| 700 | 1 | |a Kab, Sofiane |e verfasserin |4 aut | |
| 700 | 1 | |a Goldberg, Marcel |e verfasserin |4 aut | |
| 700 | 1 | |a Zins, Marie |e verfasserin |4 aut | |
| 700 | 1 | |a Lemogne, Cédric |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t BMJ mental health |d 2023 |g 27(2024), 1 vom: 15. März |w (DE-627)NLM35296488X |x 2755-9734 |7 nnns |
| 773 | 1 | 8 | |g volume:27 |g year:2024 |g number:1 |g day:15 |g month:03 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1136/bmjment-2023-300907 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 27 |j 2024 |e 1 |b 15 |c 03 | ||