New Analogues of Amides and Quinolinones Produced by Streptomyces sp. YIM S01983
© 2024 Wiley‐VHCA AG, Zurich, Switzerland..
Streptomide (1), a new amide analogue, streptomynone (2), a new quinolinone, and ten known compounds including three aliphatic acids (3-5), two amides (6-7), four cyclic dipeptides (8-11), and an adenosine (12) were isolated from the fermentation broth of Streptomyces sp. YIM S01983 isolated from a sediment sample collected in Bendong Village, Huadong Town, Chuxiong, China. Their structures were determined by analysis of the 1D/2D-NMR and HR-ESI-MS spectra. Compound 12 presented weak antimicrobial activities against Candida albicans and Aligenes faecalis (MIC=64 μg/mL). Compounds 7 and 12 showed weak cytotoxic activity against MHCC97H.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - year:2024 |
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| Enthalten in: |
Chemistry & biodiversity - (2024) vom: 14. März, Seite e202400090 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Li, Xia [VerfasserIn] |
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| Links: |
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| Themen: |
Antimicrobial activity |
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| Anmerkungen: |
Date Revised 12.04.2024 published: Print-Electronic Citation Status Publisher |
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| doi: |
10.1002/cbdv.202400090 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM369761650 |
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| 520 | |a Streptomide (1), a new amide analogue, streptomynone (2), a new quinolinone, and ten known compounds including three aliphatic acids (3-5), two amides (6-7), four cyclic dipeptides (8-11), and an adenosine (12) were isolated from the fermentation broth of Streptomyces sp. YIM S01983 isolated from a sediment sample collected in Bendong Village, Huadong Town, Chuxiong, China. Their structures were determined by analysis of the 1D/2D-NMR and HR-ESI-MS spectra. Compound 12 presented weak antimicrobial activities against Candida albicans and Aligenes faecalis (MIC=64 μg/mL). Compounds 7 and 12 showed weak cytotoxic activity against MHCC97H | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Streptomyces sp. YIM S01983 | |
| 650 | 4 | |a antimicrobial activity | |
| 650 | 4 | |a antitumor activity | |
| 650 | 4 | |a secondary metabolites | |
| 700 | 1 | |a Zhu, Dou-Ying |e verfasserin |4 aut | |
| 700 | 1 | |a Liu, Xi-Ru |e verfasserin |4 aut | |
| 700 | 1 | |a Liu, Hong-Jian |e verfasserin |4 aut | |
| 700 | 1 | |a Tang, Shu-Kun |e verfasserin |4 aut | |
| 700 | 1 | |a Cai, Le |e verfasserin |4 aut | |
| 700 | 1 | |a Zhao, Li-Xing |e verfasserin |4 aut | |
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