Does a Preoperative Bowel Regimen Change Time to Bowel Movement? A Randomized Clinical Trial
Copyright © 2024 American Urogynecologic Society. All rights reserved..
IMPORTANCE: This study is important because it aimed to assess an intervention to decrease patient discomfort after a robotic sacral colpopexy.
OBJECTIVE: Our primary outcome was to determine whether preoperative use of polyethylene glycol decreases time to first bowel movement postoperatively. Secondary outcomes include degree of pain with first bowel movement and stool consistency.
STUDY DESIGN: This was a randomized controlled trial. The experimental group was assigned polyethylene glycol daily for 7 days before surgery and the control group was not. All patients received polyethylene glycol postoperatively.
RESULTS: There was no statistically significant reduction in the time to first postoperative bowel movement when preoperative polyethylene glycol was used (mean [SD] in days for the control and experimental groups of 2.32 [0.99] and 1.96 [1.00], P = 0.21). There was a statistically significant reduction in pain levels with the first postoperative bowel movement in the experimental group (median [IQR] of 4 [2-5] vs 1 [0-2], P = 0.0007). Postoperative day 1 pain levels were also significantly lower in the experimental group (median [IQR] of 4 [3-6] vs 2 [0-4], P = 0.0484). In addition, patients had decreased average postoperative pain levels over 7 days with an estimated difference in the median pain levels of 1.88 units (95% confidence interval, 0.64-3.12; P = 0.0038).
CONCLUSIONS: Preoperative administration of polyethylene glycol did not decrease time to first postoperative bowel movement. Patients in the experimental group exhibited less pain with their first postoperative bowel movement and had improved pain levels on postoperative day 1.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2024 |
|---|---|
| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:30 |
|---|---|
| Enthalten in: |
Urogynecology (Philadelphia, Pa.) - 30(2024), 3 vom: 01. März, Seite 251-255 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Holubyeva, Anastasiya [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
3WJQ0SDW1A |
|---|
| Anmerkungen: |
Date Completed 18.03.2024 Date Revised 10.04.2024 published: Print-Electronic ClinicalTrials.gov: NCT04197869 Citation Status MEDLINE |
|---|
| doi: |
10.1097/SPV.0000000000001462 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM369739272 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM369739272 | ||
| 003 | DE-627 | ||
| 005 | 20240410232703.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 240315s2024 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1097/SPV.0000000000001462 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1371.xml |
| 035 | |a (DE-627)NLM369739272 | ||
| 035 | |a (NLM)38484239 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Holubyeva, Anastasiya |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Does a Preoperative Bowel Regimen Change Time to Bowel Movement? A Randomized Clinical Trial |
| 264 | 1 | |c 2024 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 18.03.2024 | ||
| 500 | |a Date Revised 10.04.2024 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a ClinicalTrials.gov: NCT04197869 | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2024 American Urogynecologic Society. All rights reserved. | ||
| 520 | |a IMPORTANCE: This study is important because it aimed to assess an intervention to decrease patient discomfort after a robotic sacral colpopexy | ||
| 520 | |a OBJECTIVE: Our primary outcome was to determine whether preoperative use of polyethylene glycol decreases time to first bowel movement postoperatively. Secondary outcomes include degree of pain with first bowel movement and stool consistency | ||
| 520 | |a STUDY DESIGN: This was a randomized controlled trial. The experimental group was assigned polyethylene glycol daily for 7 days before surgery and the control group was not. All patients received polyethylene glycol postoperatively | ||
| 520 | |a RESULTS: There was no statistically significant reduction in the time to first postoperative bowel movement when preoperative polyethylene glycol was used (mean [SD] in days for the control and experimental groups of 2.32 [0.99] and 1.96 [1.00], P = 0.21). There was a statistically significant reduction in pain levels with the first postoperative bowel movement in the experimental group (median [IQR] of 4 [2-5] vs 1 [0-2], P = 0.0007). Postoperative day 1 pain levels were also significantly lower in the experimental group (median [IQR] of 4 [3-6] vs 2 [0-4], P = 0.0484). In addition, patients had decreased average postoperative pain levels over 7 days with an estimated difference in the median pain levels of 1.88 units (95% confidence interval, 0.64-3.12; P = 0.0038) | ||
| 520 | |a CONCLUSIONS: Preoperative administration of polyethylene glycol did not decrease time to first postoperative bowel movement. Patients in the experimental group exhibited less pain with their first postoperative bowel movement and had improved pain levels on postoperative day 1 | ||
| 650 | 4 | |a Randomized Controlled Trial | |
| 650 | 4 | |a Journal Article | |
| 650 | 7 | |a Polyethylene Glycols |2 NLM | |
| 650 | 7 | |a 3WJQ0SDW1A |2 NLM | |
| 700 | 1 | |a Goodwin, Alexandra I |e verfasserin |4 aut | |
| 700 | 1 | |a O'Shaughnessy, Danielle |e verfasserin |4 aut | |
| 700 | 1 | |a Pillalamarri, Nirmala |e verfasserin |4 aut | |
| 700 | 1 | |a Demertzis, Kristen |e verfasserin |4 aut | |
| 700 | 1 | |a Rahbani, Ana Centeno |e verfasserin |4 aut | |
| 700 | 1 | |a Stefanov, Dimitre G |e verfasserin |4 aut | |
| 700 | 1 | |a Finamore, Peter S |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Urogynecology (Philadelphia, Pa.) |d 2022 |g 30(2024), 3 vom: 01. März, Seite 251-255 |w (DE-627)NLM340649844 |x 2771-1897 |7 nnns |
| 773 | 1 | 8 | |g volume:30 |g year:2024 |g number:3 |g day:01 |g month:03 |g pages:251-255 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1097/SPV.0000000000001462 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 30 |j 2024 |e 3 |b 01 |c 03 |h 251-255 | ||