Evaluation and post-transplant management of children after multi-organ-with-kidney transplantation

© 2024. The Author(s), under exclusive licence to International Pediatric Nephrology Association..

Multi-organ transplantation involves the transplant of two or more organs from a single donor into a single recipient; in most cases, one of these organs is a kidney. Multi-organ transplantation is uncommon in pediatric transplantation but can be life-saving or significantly life-improving for children with rare diseases, including primary heart, liver, pancreas, or intestinal failure with secondary kidney failure, metabolic disorders, and genetic conditions causing multi-organ dysfunction. This manuscript reviews the current state of pediatric multi-organ transplantation that includes a kidney, with a focus on indications, evaluation, and key differences in management compared to kidney-alone transplantation. Guidelines and consensus statements for pediatric multi-organ transplantation are nonexistent; this review condenses reported statistics and peer-reviewed expert opinion while highlighting areas in need of further research.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - year:2024

Enthalten in:

Pediatric nephrology (Berlin, Germany) - (2024) vom: 14. März

Sprache:

Englisch

Beteiligte Personen:

Engen, Rachel M [VerfasserIn]
Lemoine, Caroline P [VerfasserIn]

Links:

Volltext

Themen:

Allocation
Heart-kidney transplantation
Journal Article
Kidney-pancreas transplantation
Liver-kidney transplantation
Multi-organ transplantation
Pediatric
Review

Anmerkungen:

Date Revised 14.03.2024

published: Print-Electronic

Citation Status Publisher

doi:

10.1007/s00467-024-06336-2

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM369732928