Thrombolytic therapy after cardiac arrest in patients with mechanical aortic valve thrombosis

© 2023 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved..

A 68-year-old woman with history of aortic valve replacement developed severe heart failure and cardiac arrest. Transesophageal echocardiography and cardiac computed tomography showed mechanical aortic valve thrombosis. Low-dose, ultraslow infusion of tissue-plasminogen activator was performed while the patient was in a critically ill condition, resulting in the improvement of thrombus burden and structural valve deterioration.

Learning objectives: Mechanical valve thrombosis can be an underlying mechanism of severe heart failure, in which systemic thrombolytic therapy in a low-dose, ultraslow, and prolonged manner may improve clinical outcomes, even in critically ill patients.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:29

Enthalten in:

Journal of cardiology cases - 29(2024), 3 vom: 29. März, Seite 112-115

Sprache:

Englisch

Beteiligte Personen:

Asada, Kazunari [VerfasserIn]
Saito, Yuichi [VerfasserIn]
Kobayashi, Yoshio [VerfasserIn]

Links:

Volltext

Themen:

Case Reports
Mechanical heart valve
Prosthetic valve thrombosis
Structural valve deterioration
Thrombolytic therapy

Anmerkungen:

Date Revised 15.03.2024

published: Electronic-eCollection

Citation Status PubMed-not-MEDLINE

doi:

10.1016/j.jccase.2023.11.007

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM369713443