Comparison of analgesic effects between programmed intermittent epidural boluses and continuous epidural infusion after cesarean section : a randomized controlled study
Background: This study aimed to compare the analgesic effects of programmed intermittent epidural boluses (PIEB) and continuous epidural infusion (CEI) for postoperative analgesia after elective cesarean section (CS).
Methods: Seventy-four women who underwent elective CS were randomized to receive either PIEB or CEI. The PIEB group received 4 ml-intermittent boluses of 0.11% ropivacaine every hour at a rate of 120 ml/h. The CEI group received a constant rate of 4 ml/h of 0.11% ropivacaine. The primary outcome was the pain score at rest at 36 h after CS. Secondary outcomes included the pain scores during mobilization, time-weighted pain scores, the incidence of motor blockade, and complications-related epidural analgesia during 36 h after CS.
Results: The pain score at rest at 36 h after CS was significantly lower in the PIEB group compared with that in the CEI group (3.0 vs. 0.0; median difference, 2; 95% CI: 1, 2; P < 0.001). The mean time-weighted pain scores at rest and during mobilizations were also significantly lower in the PIEB group than in the CEI group (pain at rest: mean differences, 37.5; 95% CI, [24.6, 50.4]; P < 0.001; pain during mobilization: mean difference, 56.6; 95% CI, [39.8, 73.5]; P < 0.001). The incidence of motor blockade was significantly reduced in the PIEB group compared with that in the CEI group (P < 0.001).
Conclusion: PIEB provides superior analgesia with less motor blockade than CEI in postpartum women after CS, without any apparent adverse events.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - year:2024 |
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| Enthalten in: |
Korean journal of anesthesiology - (2024) vom: 14. März |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Bang, Yu Jeong [VerfasserIn] |
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| Links: |
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| Themen: |
Cesarean section |
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| Anmerkungen: |
Date Revised 22.03.2024 published: Print-Electronic Citation Status Publisher |
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| doi: |
10.4097/kja.23726 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM369710509 |
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| 245 | 1 | 0 | |a Comparison of analgesic effects between programmed intermittent epidural boluses and continuous epidural infusion after cesarean section |b a randomized controlled study |
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| 520 | |a Background: This study aimed to compare the analgesic effects of programmed intermittent epidural boluses (PIEB) and continuous epidural infusion (CEI) for postoperative analgesia after elective cesarean section (CS) | ||
| 520 | |a Methods: Seventy-four women who underwent elective CS were randomized to receive either PIEB or CEI. The PIEB group received 4 ml-intermittent boluses of 0.11% ropivacaine every hour at a rate of 120 ml/h. The CEI group received a constant rate of 4 ml/h of 0.11% ropivacaine. The primary outcome was the pain score at rest at 36 h after CS. Secondary outcomes included the pain scores during mobilization, time-weighted pain scores, the incidence of motor blockade, and complications-related epidural analgesia during 36 h after CS | ||
| 520 | |a Results: The pain score at rest at 36 h after CS was significantly lower in the PIEB group compared with that in the CEI group (3.0 vs. 0.0; median difference, 2; 95% CI: 1, 2; P < 0.001). The mean time-weighted pain scores at rest and during mobilizations were also significantly lower in the PIEB group than in the CEI group (pain at rest: mean differences, 37.5; 95% CI, [24.6, 50.4]; P < 0.001; pain during mobilization: mean difference, 56.6; 95% CI, [39.8, 73.5]; P < 0.001). The incidence of motor blockade was significantly reduced in the PIEB group compared with that in the CEI group (P < 0.001) | ||
| 520 | |a Conclusion: PIEB provides superior analgesia with less motor blockade than CEI in postpartum women after CS, without any apparent adverse events | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Postoperative pain | |
| 650 | 4 | |a Cesarean section | |
| 650 | 4 | |a Continuous epidural infusion | |
| 650 | 4 | |a Epidural analgesia | |
| 650 | 4 | |a Motor blockade | |
| 650 | 4 | |a Programmed intermittent epidural boluses | |
| 700 | 1 | |a Jeong, Heejoon |e verfasserin |4 aut | |
| 700 | 1 | |a Kang, RyungA |e verfasserin |4 aut | |
| 700 | 1 | |a Sung, Ji-Hee |e verfasserin |4 aut | |
| 700 | 1 | |a Choi, Suk-Joo |e verfasserin |4 aut | |
| 700 | 1 | |a Oh, Soo-Young |e verfasserin |4 aut | |
| 700 | 1 | |a Hahm, Tae Soo |e verfasserin |4 aut | |
| 700 | 1 | |a Shin, Young Hee |e verfasserin |4 aut | |
| 700 | 1 | |a Jeong, Yeon Woo |e verfasserin |4 aut | |
| 700 | 1 | |a Choi, Soo Joo |e verfasserin |4 aut | |
| 700 | 1 | |a Ko, Justin Sangwook |e verfasserin |4 aut | |
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