Virtual staining for histology by deep learning

Copyright © 2024 The Author(s). Published by Elsevier Ltd.. All rights reserved..

In pathology and biomedical research, histology is the cornerstone method for tissue analysis. Currently, the histological workflow consumes plenty of chemicals, water, and time for staining procedures. Deep learning is now enabling digital replacement of parts of the histological staining procedure. In virtual staining, histological stains are created by training neural networks to produce stained images from an unstained tissue image, or through transferring information from one stain to another. These technical innovations provide more sustainable, rapid, and cost-effective alternatives to traditional histological pipelines, but their development is in an early phase and requires rigorous validation. In this review we cover the basic concepts of virtual staining for histology and provide future insights into the utilization of artificial intelligence (AI)-enabled virtual histology.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - year:2024

Enthalten in:

Trends in biotechnology - (2024) vom: 13. März

Sprache:

Englisch

Beteiligte Personen:

Latonen, Leena [VerfasserIn]
Koivukoski, Sonja [VerfasserIn]
Khan, Umair [VerfasserIn]
Ruusuvuori, Pekka [VerfasserIn]

Links:

Volltext

Themen:

Artificial intelligence (AI)
Deep learning
Histology
Journal Article
Microscopy
Pathology
Review
Virtual staining

Anmerkungen:

Date Revised 13.03.2024

published: Print-Electronic

Citation Status Publisher

doi:

10.1016/j.tibtech.2024.02.009

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM369697340