Pre-emptive Aortic Side Branch Embolization during Endovascular Aneurysm Repair Using the Excluder Stent-Graft System : A Prospective Multicenter study
Copyright © 2024 SIR. Published by Elsevier Inc. All rights reserved..
PURPOSE: To evaluate the effectiveness and safety of pre-emptive transcatheter arterial embolization (P-TAE) for aortic side branches (ASBs) to prevent Type 2 endoleaks (EL2) before endovascular aneurysm repair (EVAR) using the Excluder stent-graft system (Excluder).
MATERIALS AND METHODS: In this prospective, multicenter study, 80 patients (mean age, 79.1 years [SD ± 6.7]; 85.0% were men; mean aneurysmal sac diameter, 48.4 mm [SD ± 7.4]) meeting the eligibility criteria were prospectively enrolled from 9 hospitals. Before EVAR, P-TAE was performed to embolize the patent ASBs originating from the abdominal aortic aneurysm. Contrast-enhanced computed tomography (CT) was performed at 1 month and 6 months after EVAR. The primary endpoint was EL2 incidence at 6 months, and the secondary endpoints were aneurysmal sac diameter changes at 6 and 12 months, P-TAE outcomes, adverse events related to P-TAE, reintervention, and aneurysm-related mortality.
RESULTS: All patients successfully underwent P-TAE without serious. Coil embolization was successful in 81.6% of ASBs. EL2 incidence at 6 months was identified in 18 of 70 (25.7%) patients. Aneurysmal sac diameter shrinkage (≥5 mm) was observed in 30.0% of patients at 6 months and in 40.9% at 12 months. Only 1 patient required reintervention for EL2 within 1 year of EVAR; aneurysm-related deaths were not observed.
CONCLUSIONS: P-TAE for ASBs before EVAR using Excluder is a safe and effective strategy. It aids in achieving early aneurysmal sac shrinkage and reduces EL2 reintervention at 1 year after EVAR.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - year:2024 |
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| Enthalten in: |
Journal of vascular and interventional radiology : JVIR - (2024) vom: 11. März |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Sasaki, Koji [VerfasserIn] |
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| Anmerkungen: |
Date Revised 13.04.2024 published: Print-Electronic Citation Status Publisher |
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| doi: |
10.1016/j.jvir.2024.01.032 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM369691652 |
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| 245 | 1 | 0 | |a Pre-emptive Aortic Side Branch Embolization during Endovascular Aneurysm Repair Using the Excluder Stent-Graft System |b A Prospective Multicenter study |
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| 500 | |a Date Revised 13.04.2024 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status Publisher | ||
| 520 | |a Copyright © 2024 SIR. Published by Elsevier Inc. All rights reserved. | ||
| 520 | |a PURPOSE: To evaluate the effectiveness and safety of pre-emptive transcatheter arterial embolization (P-TAE) for aortic side branches (ASBs) to prevent Type 2 endoleaks (EL2) before endovascular aneurysm repair (EVAR) using the Excluder stent-graft system (Excluder) | ||
| 520 | |a MATERIALS AND METHODS: In this prospective, multicenter study, 80 patients (mean age, 79.1 years [SD ± 6.7]; 85.0% were men; mean aneurysmal sac diameter, 48.4 mm [SD ± 7.4]) meeting the eligibility criteria were prospectively enrolled from 9 hospitals. Before EVAR, P-TAE was performed to embolize the patent ASBs originating from the abdominal aortic aneurysm. Contrast-enhanced computed tomography (CT) was performed at 1 month and 6 months after EVAR. The primary endpoint was EL2 incidence at 6 months, and the secondary endpoints were aneurysmal sac diameter changes at 6 and 12 months, P-TAE outcomes, adverse events related to P-TAE, reintervention, and aneurysm-related mortality | ||
| 520 | |a RESULTS: All patients successfully underwent P-TAE without serious. Coil embolization was successful in 81.6% of ASBs. EL2 incidence at 6 months was identified in 18 of 70 (25.7%) patients. Aneurysmal sac diameter shrinkage (≥5 mm) was observed in 30.0% of patients at 6 months and in 40.9% at 12 months. Only 1 patient required reintervention for EL2 within 1 year of EVAR; aneurysm-related deaths were not observed | ||
| 520 | |a CONCLUSIONS: P-TAE for ASBs before EVAR using Excluder is a safe and effective strategy. It aids in achieving early aneurysmal sac shrinkage and reduces EL2 reintervention at 1 year after EVAR | ||
| 650 | 4 | |a Journal Article | |
| 700 | 1 | |a Yamaguchi, Masato |e verfasserin |4 aut | |
| 700 | 1 | |a Gentsu, Tomoyuki |e verfasserin |4 aut | |
| 700 | 1 | |a Kawasaki, Ryota |e verfasserin |4 aut | |
| 700 | 1 | |a Miyamoto, Naokazu |e verfasserin |4 aut | |
| 700 | 1 | |a Uotani, Kensuke |e verfasserin |4 aut | |
| 700 | 1 | |a Sakamoto, Noriaki |e verfasserin |4 aut | |
| 700 | 1 | |a Fukuda, Tetsuya |e verfasserin |4 aut | |
| 700 | 1 | |a Horinouchi, Hiroki |e verfasserin |4 aut | |
| 700 | 1 | |a Taniguchi, Takanori |e verfasserin |4 aut | |
| 700 | 1 | |a Mori, Takeki |e verfasserin |4 aut | |
| 700 | 1 | |a Koda, Yojiro |e verfasserin |4 aut | |
| 700 | 1 | |a Yamanaka, Katsuhiro |e verfasserin |4 aut | |
| 700 | 1 | |a Takahashi, Hiroaki |e verfasserin |4 aut | |
| 700 | 1 | |a Okada, Kenji |e verfasserin |4 aut | |
| 700 | 1 | |a Watanabe, Toshitaka |e verfasserin |4 aut | |
| 700 | 1 | |a Hayashi, Taro |e verfasserin |4 aut | |
| 700 | 1 | |a Nomura, Yoshikatsu |e verfasserin |4 aut | |
| 700 | 1 | |a Matsushiro, Keigo |e verfasserin |4 aut | |
| 700 | 1 | |a Ueshima, Eisuke |e verfasserin |4 aut | |
| 700 | 1 | |a Okada, Takuya |e verfasserin |4 aut | |
| 700 | 1 | |a Sugimoto, Koji |e verfasserin |4 aut | |
| 700 | 1 | |a Murakami, Takamichi |e verfasserin |4 aut | |
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