Description of a national, multi-center registry of patients with sickle cell disease and SARS-CoV-2 infection : Data from the Pediatric COVID-19 United States Registry
© 2024 Wiley Periodicals LLC..
Children with sickle cell disease (SCD) are at risk of complications from viral infections, including SARS-CoV-2. We present the clinical characteristics and outcomes of pediatric patients with SCD from the Pediatric COVID-19 United States Registry who developed acute COVID-19 due to SARS-CoV-2 infection (n = 259) or multisystem inflammatory syndrome in children (MIS-C; n = 4). Nearly half of hospitalized children with SCD and SARS-CoV-2 infection required supplemental oxygen, though children with SCD had fewer intensive care (ICU) admissions compared to the general pediatric and immunocompromised populations. All registry patients with both SCD and MIS-C required ICU admission. Children with SCD are at risk of severe disease with SARS-CoV-2 infection, highlighting the importance of vaccination in this vulnerable population.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:71 |
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| Enthalten in: |
Pediatric blood & cancer - 71(2024), 6 vom: 23. Apr., Seite e30909 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Dain, Aleksandra S [VerfasserIn] |
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| Links: |
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| Themen: |
COVID |
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| Anmerkungen: |
Date Completed 24.04.2024 Date Revised 26.04.2024 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1002/pbc.30909 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM369597281 |
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| 100 | 1 | |a Dain, Aleksandra S |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Description of a national, multi-center registry of patients with sickle cell disease and SARS-CoV-2 infection |b Data from the Pediatric COVID-19 United States Registry |
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| 500 | |a Date Revised 26.04.2024 | ||
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| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2024 Wiley Periodicals LLC. | ||
| 520 | |a Children with sickle cell disease (SCD) are at risk of complications from viral infections, including SARS-CoV-2. We present the clinical characteristics and outcomes of pediatric patients with SCD from the Pediatric COVID-19 United States Registry who developed acute COVID-19 due to SARS-CoV-2 infection (n = 259) or multisystem inflammatory syndrome in children (MIS-C; n = 4). Nearly half of hospitalized children with SCD and SARS-CoV-2 infection required supplemental oxygen, though children with SCD had fewer intensive care (ICU) admissions compared to the general pediatric and immunocompromised populations. All registry patients with both SCD and MIS-C required ICU admission. Children with SCD are at risk of severe disease with SARS-CoV-2 infection, highlighting the importance of vaccination in this vulnerable population | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Multicenter Study | |
| 650 | 4 | |a COVID | |
| 650 | 4 | |a MIS‐C | |
| 650 | 4 | |a SCD | |
| 650 | 4 | |a sickle cell anemia | |
| 700 | 1 | |a Diorio, Caroline |e verfasserin |4 aut | |
| 700 | 1 | |a Fisher, Brian T |e verfasserin |4 aut | |
| 700 | 1 | |a Hankins, Jane S |e verfasserin |4 aut | |
| 700 | 1 | |a Witmer, Char M |e verfasserin |4 aut | |
| 700 | 1 | |a Boustany, Mickael |e verfasserin |4 aut | |
| 700 | 1 | |a Burton, Madeline |e verfasserin |4 aut | |
| 700 | 1 | |a Ferrolino, Jose |e verfasserin |4 aut | |
| 700 | 1 | |a Sadaf, Salma |e verfasserin |4 aut | |
| 700 | 1 | |a Ross, Hailey S |e verfasserin |4 aut | |
| 700 | 1 | |a Maron, Gabriela |e verfasserin |4 aut | |
| 700 | 0 | |a Pediatric COVID‐19 US Registry |e verfasserin |4 aut | |
| 700 | 1 | |a Ardura, Monica I |e investigator |4 oth | |
| 700 | 1 | |a Arnold, Sandra |e investigator |4 oth | |
| 700 | 1 | |a Celentano, Donna |e investigator |4 oth | |
| 700 | 1 | |a Custodio, Haidee |e investigator |4 oth | |
| 700 | 1 | |a Danziger-Isakov, Lara |e investigator |4 oth | |
| 700 | 1 | |a Enane, Leslie |e investigator |4 oth | |
| 700 | 1 | |a Foster, Catherine |e investigator |4 oth | |
| 700 | 1 | |a Furstenau, Dana |e investigator |4 oth | |
| 700 | 1 | |a Carreno, Carla Garcia |e investigator |4 oth | |
| 700 | 1 | |a Guerguis, Sandra |e investigator |4 oth | |
| 700 | 1 | |a Hammershaimb, E Adrianne |e investigator |4 oth | |
| 700 | 1 | |a Harrison, Emily |e investigator |4 oth | |
| 700 | 1 | |a Mannheim, Johnathan |e investigator |4 oth | |
| 700 | 1 | |a Mehta, Brinda |e investigator |4 oth | |
| 700 | 1 | |a Mongkolrattanothai, Kanokporn |e investigator |4 oth | |
| 700 | 1 | |a Murray, Mary |e investigator |4 oth | |
| 700 | 1 | |a Nakamura, Mari M |e investigator |4 oth | |
| 700 | 1 | |a Rathore, Mobeen |e investigator |4 oth | |
| 700 | 1 | |a Reyna, Megan |e investigator |4 oth | |
| 700 | 1 | |a Santos, Roberto P |e investigator |4 oth | |
| 700 | 1 | |a Sass, Laura |e investigator |4 oth | |
| 700 | 1 | |a Shihan, Hadeel A |e investigator |4 oth | |
| 700 | 1 | |a Smith, Michael J |e investigator |4 oth | |
| 700 | 1 | |a Statler, Victoria A |e investigator |4 oth | |
| 700 | 1 | |a Whitworth, Mary S |e investigator |4 oth | |
| 700 | 1 | |a Yarbrough, April |e investigator |4 oth | |
| 700 | 1 | |a Zhu, Frank H |e investigator |4 oth | |
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