A Skin-Inspired Self-Adaptive System for Temperature Control During Dynamic Wound Healing

© 2024. The Author(s)..

The thermoregulating function of skin that is capable of maintaining body temperature within a thermostatic state is critical. However, patients suffering from skin damage are struggling with the surrounding scene and situational awareness. Here, we report an interactive self-regulation electronic system by mimicking the human thermos-reception system. The skin-inspired self-adaptive system is composed of two highly sensitive thermistors (thermal-response composite materials), and a low-power temperature control unit (Laser-induced graphene array). The biomimetic skin can realize self-adjusting in the range of 35-42 °C, which is around physiological temperature. This thermoregulation system also contributed to skin barrier formation and wound healing. Across wound models, the treatment group healed ~ 10% more rapidly compared with the control group, and showed reduced inflammation, thus enhancing skin tissue regeneration. The skin-inspired self-adaptive system holds substantial promise for next-generation robotic and medical devices.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:16

Enthalten in:

Nano-micro letters - 16(2024), 1 vom: 11. März, Seite 152

Sprache:

Englisch

Beteiligte Personen:

Geng, Yaqi [VerfasserIn]
Chen, Guoyin [VerfasserIn]
Cao, Ran [VerfasserIn]
Dai, Hongmei [VerfasserIn]
Hu, Zexu [VerfasserIn]
Yu, Senlong [VerfasserIn]
Wang, Le [VerfasserIn]
Zhu, Liping [VerfasserIn]
Xiang, Hengxue [VerfasserIn]
Zhu, Meifang [VerfasserIn]

Links:

Volltext

Themen:

Flexible electronic system
Journal Article
Self-regulation
Thermo-reception
Wound healing

Anmerkungen:

Date Revised 14.03.2024

published: Electronic

Citation Status PubMed-not-MEDLINE

doi:

10.1007/s40820-024-01345-0

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM369562097