Features of the Reperfusion Therapy for ST-Segment Elevation Myocardial Infarction According to the Russian Registry of Acute Myocardial Infarction - REGION-IM
AIM: Based on data from the Russian REGION-IM registry, to study the features of reperfusion therapy in patients with ST-segment elevation myocardial infarction (STEMI) in real-life clinical practice.
MATERIAL AND METHODS: REGION-IM is a multicenter prospective observational study. The observational period is divided into 3 stages: during the stay in the hospital and at 6 and 12 months after inclusion in the registry. The patient's records contain demographic and history data; information about the present case of MI, including the time of the first symptom onset, first contact with medical personnel, and admission to the hospital; coronary angiography (CAG) data, percutaneous coronary intervention (PCI) data, and information about the thrombolytic therapy (TLT).
RESULTS: Reperfusion therapy was performed in 88.9 % of patients with STEMI. Primary PCI (pPCI) was performed in 60.6 % of patients. The median time from the onset of symptoms to pPCI was 315 minutes [195; 720]. The median time from ECG to pPCI was 110 minutes [84;150]. Isolated TLT was performed in 7.4 %, pharmaco-invasive treatment tactics were used only in 20.9 % of cases. The median time from ECG to TLT (prehospital and in-hospital) was 30 minutes [10; 59], whereas the median time from ECG to prehospital TLT was 18 minutes [10; 39], and in 63 % of patients, TLT was performed more than 10 minutes after diagnosis. PCI followed TLT in 73 % of patients.
CONCLUSION: The frequency of reperfusion therapy for STEMI in the Russian Federation has increased considerably in recent years. The high frequency of pPCI is noteworthy, but the timing of pPCI does not always comply with clinical guidelines. The results of this registry confirm the high demand for pharmaco-invasive strategies in real-life clinical practice. Taking into account geographical and logistical features, implementing timely myocardial reperfusion requires prehospital TLT. However, the TLT frequency in the Russian Federation is still insufficient despite its proven maximum effectiveness in the shortest possible time from the detection of acute MI.
Medienart: |
E-Artikel |
---|
Erscheinungsjahr: |
2024 |
---|---|
Erschienen: |
2024 |
Enthalten in: |
Zur Gesamtaufnahme - volume:64 |
---|---|
Enthalten in: |
Kardiologiia - 64(2024), 2 vom: 29. Feb., Seite 3-17 |
Sprache: |
Russisch |
---|
Beteiligte Personen: |
Boytsov, S A [VerfasserIn] |
---|
Links: |
---|
Themen: |
English Abstract |
---|
Anmerkungen: |
Date Completed 12.03.2024 Date Revised 21.03.2024 published: Electronic Citation Status MEDLINE |
---|
doi: |
10.18087/cardio.2024.2.n2601 |
---|
funding: |
|
---|---|
Förderinstitution / Projekttitel: |
|
PPN (Katalog-ID): |
NLM369525302 |
---|
LEADER | 01000caa a22002652 4500 | ||
---|---|---|---|
001 | NLM369525302 | ||
003 | DE-627 | ||
005 | 20240322000523.0 | ||
007 | cr uuu---uuuuu | ||
008 | 240311s2024 xx |||||o 00| ||rus c | ||
024 | 7 | |a 10.18087/cardio.2024.2.n2601 |2 doi | |
028 | 5 | 2 | |a pubmed24n1339.xml |
035 | |a (DE-627)NLM369525302 | ||
035 | |a (NLM)38462799 | ||
040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
041 | |a rus | ||
100 | 1 | |a Boytsov, S A |e verfasserin |4 aut | |
245 | 1 | 0 | |a Features of the Reperfusion Therapy for ST-Segment Elevation Myocardial Infarction According to the Russian Registry of Acute Myocardial Infarction - REGION-IM |
264 | 1 | |c 2024 | |
336 | |a Text |b txt |2 rdacontent | ||
337 | |a ƒaComputermedien |b c |2 rdamedia | ||
338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
500 | |a Date Completed 12.03.2024 | ||
500 | |a Date Revised 21.03.2024 | ||
500 | |a published: Electronic | ||
500 | |a Citation Status MEDLINE | ||
520 | |a AIM: Based on data from the Russian REGION-IM registry, to study the features of reperfusion therapy in patients with ST-segment elevation myocardial infarction (STEMI) in real-life clinical practice | ||
520 | |a MATERIAL AND METHODS: REGION-IM is a multicenter prospective observational study. The observational period is divided into 3 stages: during the stay in the hospital and at 6 and 12 months after inclusion in the registry. The patient's records contain demographic and history data; information about the present case of MI, including the time of the first symptom onset, first contact with medical personnel, and admission to the hospital; coronary angiography (CAG) data, percutaneous coronary intervention (PCI) data, and information about the thrombolytic therapy (TLT) | ||
520 | |a RESULTS: Reperfusion therapy was performed in 88.9 % of patients with STEMI. Primary PCI (pPCI) was performed in 60.6 % of patients. The median time from the onset of symptoms to pPCI was 315 minutes [195; 720]. The median time from ECG to pPCI was 110 minutes [84;150]. Isolated TLT was performed in 7.4 %, pharmaco-invasive treatment tactics were used only in 20.9 % of cases. The median time from ECG to TLT (prehospital and in-hospital) was 30 minutes [10; 59], whereas the median time from ECG to prehospital TLT was 18 minutes [10; 39], and in 63 % of patients, TLT was performed more than 10 minutes after diagnosis. PCI followed TLT in 73 % of patients | ||
520 | |a CONCLUSION: The frequency of reperfusion therapy for STEMI in the Russian Federation has increased considerably in recent years. The high frequency of pPCI is noteworthy, but the timing of pPCI does not always comply with clinical guidelines. The results of this registry confirm the high demand for pharmaco-invasive strategies in real-life clinical practice. Taking into account geographical and logistical features, implementing timely myocardial reperfusion requires prehospital TLT. However, the TLT frequency in the Russian Federation is still insufficient despite its proven maximum effectiveness in the shortest possible time from the detection of acute MI | ||
650 | 4 | |a English Abstract | |
650 | 4 | |a Journal Article | |
650 | 4 | |a Multicenter Study | |
650 | 4 | |a Observational Study | |
700 | 1 | |a Shakhnovich, R M |e verfasserin |4 aut | |
700 | 1 | |a Tereschenko, S N |e verfasserin |4 aut | |
700 | 1 | |a Erlikh, A D |e verfasserin |4 aut | |
700 | 1 | |a Pevsner, D V |e verfasserin |4 aut | |
700 | 1 | |a Gulyan, R G |e verfasserin |4 aut | |
700 | 1 | |a Rytova, Yu K |e verfasserin |4 aut | |
700 | 1 | |a Dmitrieva, N Yu |e verfasserin |4 aut | |
700 | 1 | |a Voznyuk, Ya M |e verfasserin |4 aut | |
700 | 1 | |a Musikhina, N A |e verfasserin |4 aut | |
700 | 1 | |a Nazarova, O A |e verfasserin |4 aut | |
700 | 1 | |a Pogorelova, N A |e verfasserin |4 aut | |
700 | 1 | |a Sanabasova, G K |e verfasserin |4 aut | |
700 | 1 | |a Sviridova, A V |e verfasserin |4 aut | |
700 | 1 | |a Sukhareva, I V |e verfasserin |4 aut | |
700 | 1 | |a Filinova, A S |e verfasserin |4 aut | |
700 | 1 | |a Shylko, Yu V |e verfasserin |4 aut | |
700 | 1 | |a Shirikova, G A |e verfasserin |4 aut | |
773 | 0 | 8 | |i Enthalten in |t Kardiologiia |d 1961 |g 64(2024), 2 vom: 29. Feb., Seite 3-17 |w (DE-627)NLM000007153 |x 0022-9040 |7 nnns |
773 | 1 | 8 | |g volume:64 |g year:2024 |g number:2 |g day:29 |g month:02 |g pages:3-17 |
856 | 4 | 0 | |u http://dx.doi.org/10.18087/cardio.2024.2.n2601 |3 Volltext |
912 | |a GBV_USEFLAG_A | ||
912 | |a GBV_NLM | ||
951 | |a AR | ||
952 | |d 64 |j 2024 |e 2 |b 29 |c 02 |h 3-17 |