Value of the modified Patient-Generated Subjective Global Assessment in indicating the need for nutrition intervention and predicting overall survival in patients with malignant tumors in at least two organs
© 2024 American Society for Parenteral and Enteral Nutrition..
BACKGROUND: Although the Patient-Generated Subjective Global Assessment (PG-SGA) is a reference standard used to assess a patient's nutrition status, it is cumbersome to administer. The aim of the present study was to estimate the value of a simpler and easier-to-use modified PG-SGA (mPG-SGA) to evaluate the nutrition status and need for intervention in patients with malignant tumors present in at least two organs.
METHODS: A total of 591 patients (343 male and 248 female) were included from the INSCOC study. A Pearson correlation analysis was conducted to assess the correlation between the mPG-SGA and nutrition-related factors, with the optimal cut-off defined by a receiver operating characteristic curve (ROC). The consistency between the mPG-SGA and PG-SGA was compared in a concordance analysis. A survival analysis was used to determine the effects of nutritional intervention among different nutrition status groups. Univariable and multivariable Cox analyses were applied to evaluate the association of the mPG-SGA with the all-cause mortality.
RESULTS: The mPG-SGA showed a negative association with nutrition-related factors. Individuals with an mPG-SGA ≥ 5 (rounded from 4.5) were considered to need nutritional intervention. Among the malnourished patients (mPG-SGA ≥ 5), the overall survival (OS) of those who received nutrition intervention was significantly higher than that of patients who did not. However, the OS was not significantly different in the better-nourished patients (mPG-SGA < 5).
CONCLUSION: Our findings support that the mPG-SGA is a feasible tool that can be used to guide nutritional interventions and predict the survival of patients with malignant tumors affecting at least two organs.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - year:2024 |
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| Enthalten in: |
Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition - (2024) vom: 09. März |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Chong, Feifei [VerfasserIn] |
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| Links: |
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| Themen: |
Cancer |
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| Anmerkungen: |
Date Revised 09.03.2024 published: Print-Electronic Citation Status Publisher |
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| doi: |
10.1002/ncp.11140 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM36950691X |
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| 041 | |a eng | ||
| 100 | 1 | |a Chong, Feifei |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Value of the modified Patient-Generated Subjective Global Assessment in indicating the need for nutrition intervention and predicting overall survival in patients with malignant tumors in at least two organs |
| 264 | 1 | |c 2024 | |
| 336 | |a Text |b txt |2 rdacontent | ||
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| 500 | |a Date Revised 09.03.2024 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status Publisher | ||
| 520 | |a © 2024 American Society for Parenteral and Enteral Nutrition. | ||
| 520 | |a BACKGROUND: Although the Patient-Generated Subjective Global Assessment (PG-SGA) is a reference standard used to assess a patient's nutrition status, it is cumbersome to administer. The aim of the present study was to estimate the value of a simpler and easier-to-use modified PG-SGA (mPG-SGA) to evaluate the nutrition status and need for intervention in patients with malignant tumors present in at least two organs | ||
| 520 | |a METHODS: A total of 591 patients (343 male and 248 female) were included from the INSCOC study. A Pearson correlation analysis was conducted to assess the correlation between the mPG-SGA and nutrition-related factors, with the optimal cut-off defined by a receiver operating characteristic curve (ROC). The consistency between the mPG-SGA and PG-SGA was compared in a concordance analysis. A survival analysis was used to determine the effects of nutritional intervention among different nutrition status groups. Univariable and multivariable Cox analyses were applied to evaluate the association of the mPG-SGA with the all-cause mortality | ||
| 520 | |a RESULTS: The mPG-SGA showed a negative association with nutrition-related factors. Individuals with an mPG-SGA ≥ 5 (rounded from 4.5) were considered to need nutritional intervention. Among the malnourished patients (mPG-SGA ≥ 5), the overall survival (OS) of those who received nutrition intervention was significantly higher than that of patients who did not. However, the OS was not significantly different in the better-nourished patients (mPG-SGA < 5) | ||
| 520 | |a CONCLUSION: Our findings support that the mPG-SGA is a feasible tool that can be used to guide nutritional interventions and predict the survival of patients with malignant tumors affecting at least two organs | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a cancer | |
| 650 | 4 | |a malnutrition | |
| 650 | 4 | |a nutrition assessment | |
| 650 | 4 | |a nutrition status | |
| 650 | 4 | |a survival | |
| 700 | 1 | |a Huo, Zhenyu |e verfasserin |4 aut | |
| 700 | 1 | |a Yin, Liangyu |e verfasserin |4 aut | |
| 700 | 1 | |a Liu, Jie |e verfasserin |4 aut | |
| 700 | 1 | |a Li, Na |e verfasserin |4 aut | |
| 700 | 1 | |a Guo, Jing |e verfasserin |4 aut | |
| 700 | 1 | |a Fan, Yang |e verfasserin |4 aut | |
| 700 | 1 | |a Zhang, Mengyuan |e verfasserin |4 aut | |
| 700 | 1 | |a Zhang, Ling |e verfasserin |4 aut | |
| 700 | 1 | |a Lin, Xin |e verfasserin |4 aut | |
| 700 | 1 | |a Chen, Junqiang |e verfasserin |4 aut | |
| 700 | 1 | |a Zhou, Chunling |e verfasserin |4 aut | |
| 700 | 1 | |a Li, Suyi |e verfasserin |4 aut | |
| 700 | 1 | |a Zhou, Fuxiang |e verfasserin |4 aut | |
| 700 | 1 | |a Yao, Qinghua |e verfasserin |4 aut | |
| 700 | 1 | |a Guo, Zengqing |e verfasserin |4 aut | |
| 700 | 1 | |a Weng, Min |e verfasserin |4 aut | |
| 700 | 1 | |a Liu, Ming |e verfasserin |4 aut | |
| 700 | 1 | |a Li, Tao |e verfasserin |4 aut | |
| 700 | 1 | |a Li, Zengning |e verfasserin |4 aut | |
| 700 | 1 | |a Cui, Jiuwei |e verfasserin |4 aut | |
| 700 | 1 | |a Li, Wei |e verfasserin |4 aut | |
| 700 | 1 | |a Shi, Hanping |e verfasserin |4 aut | |
| 700 | 1 | |a Guo, Wei |e verfasserin |4 aut | |
| 700 | 1 | |a Xu, Hongxia |e verfasserin |4 aut | |
| 700 | 0 | |a Investigation on Nutrition Status and Clinical Outcome of Common Cancers (INSCOC) Group |e verfasserin |4 aut | |
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