Susceptibility of hypertensive individuals to acute blood pressure increases in response to personal-level environmental temperature decrease
Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved..
BACKGROUND: Environmental temperature is negatively associated with blood pressure (BP), and hypertension may exacerbate this association. The aim of this study is to investigate whether hypertensive individuals are more susceptible to acute BP increases following temperature decrease than non-hypertensive individuals.
METHODS: The study panel consisted of 126 hypertensive and 125 non-hypertensive (n = 251) elderly participants who completed 940 clinical visits during the winter of 2016 and summer of 2017 in Beijing, China. Personal-level environmental temperature (PET) was continuously monitored for each participant with a portable sensor platform. We associated systolic BP (SBP) and diastolic BP (DBP) with the average PET over 24 h before clinical visits using linear mixed-effects models and explored hourly lag patterns for the associations using distributed lag models.
RESULTS: We found that per 1 °C decrease in PET, hypertensive individuals showed an average (95 % confidence interval) increase of 0.96 (0.72, 1.19) and 0.28 (0.13, 0.42) mmHg for SBP and DBP, respectively; and non-hypertensive participants showed significantly smaller increases of 0.28 (0.03, 0.53) mmHg SBP and 0.14 (-0.01, 0.30) mmHg DBP. A lag pattern analysis showed that for hypertensive individuals, the increases in SBP and DBP were greatest following lag 1 h PET decrease and gradually attenuated up to lag 10 h exposure. No significant BP change was observed in non-hypertensive individuals associated with lag 1-24 h PET exposure. The enhanced increase in PET-associated BP in hypertensive participants (i.e., susceptibility) was more significant in winter than in summer.
CONCLUSIONS: We found that a decrease in environmental temperature was associated with acute BP increases and these associations diminished over time, disappearing after approximately 10 hours. This implies that any intervention measures to prevent BP increases due to temperature drop should be implemented as soon as possible. Such timely interventions are particularly needed for hypertensive individuals especially during the cold season due to their increased susceptibility.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:185 |
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| Enthalten in: |
Environment international - 185(2024) vom: 26. März, Seite 108567 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Xu, Yifan [VerfasserIn] |
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| Links: |
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| Themen: |
Blood pressure |
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| Anmerkungen: |
Date Completed 26.03.2024 Date Revised 26.03.2024 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.envint.2024.108567 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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NLM369499700 |
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| 100 | 1 | |a Xu, Yifan |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Susceptibility of hypertensive individuals to acute blood pressure increases in response to personal-level environmental temperature decrease |
| 264 | 1 | |c 2024 | |
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| 500 | |a Date Revised 26.03.2024 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved. | ||
| 520 | |a BACKGROUND: Environmental temperature is negatively associated with blood pressure (BP), and hypertension may exacerbate this association. The aim of this study is to investigate whether hypertensive individuals are more susceptible to acute BP increases following temperature decrease than non-hypertensive individuals | ||
| 520 | |a METHODS: The study panel consisted of 126 hypertensive and 125 non-hypertensive (n = 251) elderly participants who completed 940 clinical visits during the winter of 2016 and summer of 2017 in Beijing, China. Personal-level environmental temperature (PET) was continuously monitored for each participant with a portable sensor platform. We associated systolic BP (SBP) and diastolic BP (DBP) with the average PET over 24 h before clinical visits using linear mixed-effects models and explored hourly lag patterns for the associations using distributed lag models | ||
| 520 | |a RESULTS: We found that per 1 °C decrease in PET, hypertensive individuals showed an average (95 % confidence interval) increase of 0.96 (0.72, 1.19) and 0.28 (0.13, 0.42) mmHg for SBP and DBP, respectively; and non-hypertensive participants showed significantly smaller increases of 0.28 (0.03, 0.53) mmHg SBP and 0.14 (-0.01, 0.30) mmHg DBP. A lag pattern analysis showed that for hypertensive individuals, the increases in SBP and DBP were greatest following lag 1 h PET decrease and gradually attenuated up to lag 10 h exposure. No significant BP change was observed in non-hypertensive individuals associated with lag 1-24 h PET exposure. The enhanced increase in PET-associated BP in hypertensive participants (i.e., susceptibility) was more significant in winter than in summer | ||
| 520 | |a CONCLUSIONS: We found that a decrease in environmental temperature was associated with acute BP increases and these associations diminished over time, disappearing after approximately 10 hours. This implies that any intervention measures to prevent BP increases due to temperature drop should be implemented as soon as possible. Such timely interventions are particularly needed for hypertensive individuals especially during the cold season due to their increased susceptibility | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Blood pressure | |
| 650 | 4 | |a Hypertension | |
| 650 | 4 | |a Personal-level environmental temperature | |
| 650 | 4 | |a Susceptibility | |
| 700 | 1 | |a Han, Yiqun |e verfasserin |4 aut | |
| 700 | 1 | |a Chen, Wu |e verfasserin |4 aut | |
| 700 | 1 | |a Chatzidiakou, Lia |e verfasserin |4 aut | |
| 700 | 1 | |a Yan, Li |e verfasserin |4 aut | |
| 700 | 1 | |a Krause, Anika |e verfasserin |4 aut | |
| 700 | 1 | |a Li, Yilin |e verfasserin |4 aut | |
| 700 | 1 | |a Zhang, Hanbin |e verfasserin |4 aut | |
| 700 | 1 | |a Wang, Teng |e verfasserin |4 aut | |
| 700 | 1 | |a Xue, Tao |e verfasserin |4 aut | |
| 700 | 1 | |a Chan, Queenie |e verfasserin |4 aut | |
| 700 | 1 | |a Barratt, Ben |e verfasserin |4 aut | |
| 700 | 1 | |a Jones, Roderic L |e verfasserin |4 aut | |
| 700 | 1 | |a Liu, Jing |e verfasserin |4 aut | |
| 700 | 1 | |a Wu, Yangfeng |e verfasserin |4 aut | |
| 700 | 1 | |a Zhao, Meiping |e verfasserin |4 aut | |
| 700 | 1 | |a Zhang, Junfeng |e verfasserin |4 aut | |
| 700 | 1 | |a Kelly, Frank J |e verfasserin |4 aut | |
| 700 | 1 | |a Zhu, Tong |e verfasserin |4 aut | |
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