A Novel Approach for Mixed-Methods Research Using Large Language Models : A Report Using Patients' Perspectives on Barriers to Arthroplasty

© 2024 The Authors. ACR Open Rheumatology published by Wiley Periodicals LLC on behalf of American College of Rheumatology..

OBJECTIVE: Mixed-methods research is valuable in health care to gain insights into patient perceptions. However, analyzing textual data from interviews can be time-consuming and require multiple analysts for investigator triangulation. This study aims to explore a novel approach to investigator triangulation in mixed-methods research by employing a large language model (LLM) for analyzing data from patient interviews.

METHODS: This study compared the thematic analysis and survey generation performed by human investigators and ChatGPT-4, which uses GPT-4 as its backbone model, using data from an existing study that explored patient perceptions of barriers to arthroplasty. The human- and ChatGPT-4-generated themes and surveys were compared and evaluated based on their representation of salient themes from a predetermined topic guide.

RESULTS: ChatGPT-4 generated analogous dominant themes and a comprehensive corresponding survey as the human investigators but in significantly less time. The survey questions generated by ChatGPT-4 were less precise than those developed by human investigators. The mixed-methods flowchart proposes integrating LLMs and human investigators as a supplementary tool for the preliminary thematic analysis of qualitative data and survey generation.

CONCLUSION: By utilizing a combination of LLMs and human investigators through investigator triangulation, researchers may be able to conduct more efficient mixed-methods research to better understand patient perspectives. Ethical and qualitative implications of using LLMs should be considered.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - year:2024

Enthalten in:

ACR open rheumatology - (2024) vom: 07. März

Sprache:

Englisch

Beteiligte Personen:

Mannstadt, Insa [VerfasserIn]
Goodman, Susan M [VerfasserIn]
Rajan, Mangala [VerfasserIn]
Young, Sarah R [VerfasserIn]
Wang, Fei [VerfasserIn]
Navarro-Millán, Iris [VerfasserIn]
Mehta, Bella [VerfasserIn]

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Journal Article

Anmerkungen:

Date Revised 07.03.2024

published: Print-Electronic

Citation Status Publisher

doi:

10.1002/acr2.11662

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM369439163