A Low-Protein, Plant-Dominant Gluten-Free Diet for Immunoglobulin A Nephropathy and Focal Segmental Glomerulosclerosis

Copyright © 2023 National Kidney Foundation, Inc. All rights reserved..

Immunoglobulin A nephropathy is the most common glomerulonephritis syndrome in the world, yet there is currently no cure. While blood pressure control, renin-angiotensin-aldosterone system inhibition, and immunosuppression may slow disease progression, low-protein diets, defined as a daily dietary protein intake of 0.6 to 0.8 g/kg body weight, may also decrease immune complex deposition and disease severity, as evidenced in animal models. The link between secondary immunoglobulin A nephropathy and celiac disease has also led to the rise of gluten-free diets and zinc supplementation as potential lifestyle modifications to help manage common immunoglobulin A nephropathy symptoms such as proteinuria and hematuria. In addition, case reports and prospective studies suggest that patients with focal segmental glomerulosclerosis, which manifests as steroid-resistant nephrotic syndrome may also benefit from a gluten-free diet. We highlight the example of a gluten-free, plant-dominant low-protein diet (a different type of low-protein diet that addresses both protein quantity and quality) for patients with immunoglobulin A nephropathy or focal segmental glomerulosclerosis.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - volume:30

Enthalten in:

Advances in kidney disease and health - 30(2023), 6 vom: 07. Nov., Seite 517-522

Sprache:

Englisch

Beteiligte Personen:

Patel, Jason [VerfasserIn]
Kalantar-Zadeh, Kamyar [VerfasserIn]
Betz, Melanie [VerfasserIn]
Joshi, Shivam [VerfasserIn]

Links:

Volltext

Themen:

Dietary Proteins
Focal segmental glomerulosclerosis (FSGS)
Gluten, Diet
IgA nephropathy
Journal Article
Plant Proteins
Plant dominant low protein (PLADO)
Review

Anmerkungen:

Date Completed 11.03.2024

Date Revised 11.03.2024

published: Print

Citation Status MEDLINE

doi:

10.1053/j.akdh.2023.09.001

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM369430182