Accuracy of rapid blood coagulation testing device FibCare® in a tertiary emergency department
© 2024 The Authors. Acute Medicine & Surgery published by John Wiley & Sons Australia, Ltd on behalf of Japanese Association for Acute Medicine..
Aim: FibCare® is a novel point-of-care testing device enabling prompt evaluation of fibrinogen levels. This study aimed to investigate the accuracy of FibCare® at a tertiary emergency department.
Methods: Blood specimens obtained at a tertiary emergency medical center between October 1, 2021, and April 30, 2023, were evaluated. The correlation between the fibrinogen levels assessed via FibCare® and those via the Clauss method was evaluated using the Spearman's test. The discrepancy between the two measurement methods was assessed according to fibrinogen level and diagnosis.
Results: A total of 177 specimens from 147 patients were eligible for the analysis. The median age of the patients was 49 years, and 109 (61.6%) were men. The two measurements had statistically significant but moderate correlation (p < 0.001, ρ = 0.76). FibCare® missed 14 out of 35 cases from patients with hypofibrinogenemia (fibrinogen ≤150 mg/dL assessed by the Clauss method). The discrepancy between the two measurements was significantly greater in specimens with lower fibrinogen levels and those obtained from patients following trauma.
Conclusions: FibCare®, a novel point-of-care testing device, can be compatible with the Clauss method. However, clinicians should be aware of the risk that FibCare® may underestimate fibrinogen reduction, especially in severe cases and trauma cases.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2024 |
|---|---|
| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:11 |
|---|---|
| Enthalten in: |
Acute medicine & surgery - 11(2024), 1 vom: 04. Jan., Seite e934 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Mihara, Yutaka [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Blood coagulation |
|---|
| Anmerkungen: |
Date Revised 08.03.2024 published: Electronic-eCollection Citation Status PubMed-not-MEDLINE |
|---|
| doi: |
10.1002/ams2.934 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM369398025 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM369398025 | ||
| 003 | DE-627 | ||
| 005 | 20240308232934.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 240307s2024 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1002/ams2.934 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1320.xml |
| 035 | |a (DE-627)NLM369398025 | ||
| 035 | |a (NLM)38450033 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Mihara, Yutaka |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Accuracy of rapid blood coagulation testing device FibCare® in a tertiary emergency department |
| 264 | 1 | |c 2024 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Revised 08.03.2024 | ||
| 500 | |a published: Electronic-eCollection | ||
| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a © 2024 The Authors. Acute Medicine & Surgery published by John Wiley & Sons Australia, Ltd on behalf of Japanese Association for Acute Medicine. | ||
| 520 | |a Aim: FibCare® is a novel point-of-care testing device enabling prompt evaluation of fibrinogen levels. This study aimed to investigate the accuracy of FibCare® at a tertiary emergency department | ||
| 520 | |a Methods: Blood specimens obtained at a tertiary emergency medical center between October 1, 2021, and April 30, 2023, were evaluated. The correlation between the fibrinogen levels assessed via FibCare® and those via the Clauss method was evaluated using the Spearman's test. The discrepancy between the two measurement methods was assessed according to fibrinogen level and diagnosis | ||
| 520 | |a Results: A total of 177 specimens from 147 patients were eligible for the analysis. The median age of the patients was 49 years, and 109 (61.6%) were men. The two measurements had statistically significant but moderate correlation (p < 0.001, ρ = 0.76). FibCare® missed 14 out of 35 cases from patients with hypofibrinogenemia (fibrinogen ≤150 mg/dL assessed by the Clauss method). The discrepancy between the two measurements was significantly greater in specimens with lower fibrinogen levels and those obtained from patients following trauma | ||
| 520 | |a Conclusions: FibCare®, a novel point-of-care testing device, can be compatible with the Clauss method. However, clinicians should be aware of the risk that FibCare® may underestimate fibrinogen reduction, especially in severe cases and trauma cases | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a blood coagulation | |
| 650 | 4 | |a diagnosis | |
| 650 | 4 | |a emergency room | |
| 650 | 4 | |a fibrinogen | |
| 650 | 4 | |a trauma | |
| 700 | 1 | |a Komoriya, Kenta |e verfasserin |4 aut | |
| 700 | 1 | |a Hagiwara, Kei |e verfasserin |4 aut | |
| 700 | 1 | |a Hatanaka, Yasuhito |e verfasserin |4 aut | |
| 700 | 1 | |a Shibahashi, Keita |e verfasserin |4 aut | |
| 700 | 1 | |a Hikone, Mayu |e verfasserin |4 aut | |
| 700 | 1 | |a Sugiyama, Kazuhiro |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Acute medicine & surgery |d 2014 |g 11(2024), 1 vom: 04. Jan., Seite e934 |w (DE-627)NLM26868071X |x 2052-8817 |7 nnns |
| 773 | 1 | 8 | |g volume:11 |g year:2024 |g number:1 |g day:04 |g month:01 |g pages:e934 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1002/ams2.934 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 11 |j 2024 |e 1 |b 04 |c 01 |h e934 | ||