A retrospective study describing the effective exchange of total blood plasma for disease control in the exacerbation of serpiginous choroiditis
© 2024 International Society for Apheresis and Japanese Society for Apheresis..
INTRODUCTION: Serpiginous choroiditis presents with large yellow-white exudative lesions that occur near the optic nerve papillae, that progresses slowly with repeated relapses and cures. Although infection and autoimmunity have been implicated, the cause is unknown.
METHODS: A man was diagnosed with serpiginous choroiditis on clinical and other examinations. He started treatment with oral corticosteroids, cyclophosphamide, adalimumab, azathioprine, rituximab, and mycophenolate mofetil. Only the steroids and cyclophosphamide had a therapeutic effect. Plasma exchange was initiated, and the lesions quickly resolved.
RESULTS: Disease control has been maintained by plasma exchange and cyclophosphamide during flare-ups in the fall and winter, suggesting that plasma exchange is effective in the treatment of serpiginous choroiditis.
CONCLUSION: The reproducible response with each recurrence suggests a strong association between the disease and autoimmunity. Furthermore, that some, as yet unknown, autoantibodies are involved in the pathogenesis of serpiginous choroiditis.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - year:2024 |
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| Enthalten in: |
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy - (2024) vom: 06. März |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Katayama, Yuri [VerfasserIn] |
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| Links: |
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| Themen: |
Cyclophosphamide |
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| Anmerkungen: |
Date Revised 06.03.2024 published: Print-Electronic Citation Status Publisher |
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| doi: |
10.1111/1744-9987.14116 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM369380487 |
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| 100 | 1 | |a Katayama, Yuri |e verfasserin |4 aut | |
| 245 | 1 | 2 | |a A retrospective study describing the effective exchange of total blood plasma for disease control in the exacerbation of serpiginous choroiditis |
| 264 | 1 | |c 2024 | |
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| 500 | |a Date Revised 06.03.2024 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status Publisher | ||
| 520 | |a © 2024 International Society for Apheresis and Japanese Society for Apheresis. | ||
| 520 | |a INTRODUCTION: Serpiginous choroiditis presents with large yellow-white exudative lesions that occur near the optic nerve papillae, that progresses slowly with repeated relapses and cures. Although infection and autoimmunity have been implicated, the cause is unknown | ||
| 520 | |a METHODS: A man was diagnosed with serpiginous choroiditis on clinical and other examinations. He started treatment with oral corticosteroids, cyclophosphamide, adalimumab, azathioprine, rituximab, and mycophenolate mofetil. Only the steroids and cyclophosphamide had a therapeutic effect. Plasma exchange was initiated, and the lesions quickly resolved | ||
| 520 | |a RESULTS: Disease control has been maintained by plasma exchange and cyclophosphamide during flare-ups in the fall and winter, suggesting that plasma exchange is effective in the treatment of serpiginous choroiditis | ||
| 520 | |a CONCLUSION: The reproducible response with each recurrence suggests a strong association between the disease and autoimmunity. Furthermore, that some, as yet unknown, autoantibodies are involved in the pathogenesis of serpiginous choroiditis | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a cyclophosphamide | |
| 650 | 4 | |a plasma exchange | |
| 650 | 4 | |a serpiginous choroiditis | |
| 700 | 1 | |a Katagiri, Daisuke |e verfasserin |4 aut | |
| 700 | 1 | |a Harada, Takuya |e verfasserin |4 aut | |
| 700 | 1 | |a Terakawa, Kanako |e verfasserin |4 aut | |
| 700 | 1 | |a Shimada, Keiki |e verfasserin |4 aut | |
| 700 | 1 | |a Sakamoto, Emi |e verfasserin |4 aut | |
| 700 | 1 | |a Niikura, Takahito |e verfasserin |4 aut | |
| 700 | 1 | |a Suzuki, Minami |e verfasserin |4 aut | |
| 700 | 1 | |a Yoshizaki, Yuki |e verfasserin |4 aut | |
| 700 | 1 | |a Nunose, Naoto |e verfasserin |4 aut | |
| 700 | 1 | |a Sato, Motohiko |e verfasserin |4 aut | |
| 700 | 1 | |a Yashiro, Shigeko |e verfasserin |4 aut | |
| 700 | 1 | |a Kaneko, Hiroshi |e verfasserin |4 aut | |
| 700 | 1 | |a Takano, Hideki |e verfasserin |4 aut | |
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