Generation of an induced pluripotent stem cell line (KNIHi001-A) by reprogramming peripheral blood mononuclear cells isolated from a patient with Parkinson's disease
Copyright © 2024 The Authors. Published by Elsevier B.V. All rights reserved..
Parkinson's disease is a degenerative brain disorder characterized by dopamine neuronal degeneration and dopamine transporter loss. In this study, we generated an induced pluripotent stem cell (iPSC) line, KNIHi001-A, from the peripheral blood mononuclear cells (PBMCs) of a 76-year-old man with Parkinson's disease. The non-integrating Sendai virus was used to reprogram iPSCs. iPSCs exhibit pluripotent markers, a normal karyotype, viral clearance, and the ability to differentiate into the three germ layers.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:76 |
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| Enthalten in: |
Stem cell research - 76(2024) vom: 30. März, Seite 103358 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Baek, Daye [VerfasserIn] |
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Date Completed 25.03.2024 Date Revised 25.03.2024 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.scr.2024.103358 |
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| 520 | |a Parkinson's disease is a degenerative brain disorder characterized by dopamine neuronal degeneration and dopamine transporter loss. In this study, we generated an induced pluripotent stem cell (iPSC) line, KNIHi001-A, from the peripheral blood mononuclear cells (PBMCs) of a 76-year-old man with Parkinson's disease. The non-integrating Sendai virus was used to reprogram iPSCs. iPSCs exhibit pluripotent markers, a normal karyotype, viral clearance, and the ability to differentiate into the three germ layers | ||
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| 700 | 1 | |a Park, Jung Hyun |e verfasserin |4 aut | |
| 700 | 1 | |a Lee, Hye-Kyung |e verfasserin |4 aut | |
| 700 | 1 | |a Bayarsaikhan, Govigerel |e verfasserin |4 aut | |
| 700 | 1 | |a Yoo, Sang-Won |e verfasserin |4 aut | |
| 700 | 1 | |a Lee, Bonghee |e verfasserin |4 aut | |
| 700 | 1 | |a Kim, Joong-Seok |e verfasserin |4 aut | |
| 700 | 1 | |a Koh, Young Ho |e verfasserin |4 aut | |
| 700 | 1 | |a Kwon, Munjin |e verfasserin |4 aut | |
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