Predictors of successful primary antegrade wiring in chronic total occlusion percutaneous coronary intervention
BACKGROUND: Antegrade wiring is the most commonly used chronic total occlusion (CTO) crossing technique.
METHODS: Using data from the PROGRESS CTO registry (Prospective Global Registry for the Study of Chronic Total Occlusion Intervention; Clinicaltrials.gov identifier: NCT02061436), we examined the clinical and angiographic characteristics and procedural outcomes of CTO percutaneous coronary interventions (PCIs) performed using a primary antegrade wiring strategy.
RESULTS: Of the 13 563 CTO PCIs performed at 46 centers between 2012 and 2023, a primary antegrade wiring strategy was used in 11 332 (83.6%). Upon multivariable logistic regression analysis, proximal cap ambiguity (odds ratio [OR]: 0.52; 95% CI, 0.46-0.59), side branch at the proximal cap (OR: 0.85; 95% CI, 0.77-0.95), blunt/no stump (OR: 0.52; 95% CI: 0.47-0.59), increasing lesion length (OR [per 10 mm increase]: 0.79; 95% CI, 0.76-0.81), moderate to severe calcification (OR: 0.73; 95% CI, 0.66-0.81), moderate to severe proximal tortuosity (OR: 0.67; 95% CI, 0.59-0.75), bifurcation at the distal cap (OR: 0.66; 95% CI, 0.59-0.73), left anterior descending artery CTO (OR [vs right coronary artery]: 1.44; 95% CI, 1.28-1.62) and left circumflex CTO (OR [vs right coronary artery]: 1.22; 95% CI, 1.07-1.40), non-in-stent restenosis lesion (OR: 0.56; 95% CI, 0.49-0.65), and good distal landing zone (OR: 1.18; 95% CI, 1.06-1.32) were independently associated with primary antegrade wiring crossing success.
CONCLUSIONS: The use of antegrade wiring as the initial strategy was high (83.6%) in our registry. We identified several parameters associated with primary antegrade wiring success.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - year:2024 |
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| Enthalten in: |
The Journal of invasive cardiology - (2024) vom: 29. Feb. |
| Sprache: |
Englisch |
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| Links: |
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| Themen: |
Antegrade wiring |
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| Anmerkungen: |
Date Revised 06.03.2024 published: Print-Electronic ClinicalTrials.gov: NCT02061436 Citation Status Publisher |
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| doi: |
10.25270/jic/23.00305 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM369358538 |
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| 100 | 1 | |a Rempakos, Athanasios |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Predictors of successful primary antegrade wiring in chronic total occlusion percutaneous coronary intervention |
| 264 | 1 | |c 2024 | |
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| 500 | |a Date Revised 06.03.2024 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a ClinicalTrials.gov: NCT02061436 | ||
| 500 | |a Citation Status Publisher | ||
| 520 | |a BACKGROUND: Antegrade wiring is the most commonly used chronic total occlusion (CTO) crossing technique | ||
| 520 | |a METHODS: Using data from the PROGRESS CTO registry (Prospective Global Registry for the Study of Chronic Total Occlusion Intervention; Clinicaltrials.gov identifier: NCT02061436), we examined the clinical and angiographic characteristics and procedural outcomes of CTO percutaneous coronary interventions (PCIs) performed using a primary antegrade wiring strategy | ||
| 520 | |a RESULTS: Of the 13 563 CTO PCIs performed at 46 centers between 2012 and 2023, a primary antegrade wiring strategy was used in 11 332 (83.6%). Upon multivariable logistic regression analysis, proximal cap ambiguity (odds ratio [OR]: 0.52; 95% CI, 0.46-0.59), side branch at the proximal cap (OR: 0.85; 95% CI, 0.77-0.95), blunt/no stump (OR: 0.52; 95% CI: 0.47-0.59), increasing lesion length (OR [per 10 mm increase]: 0.79; 95% CI, 0.76-0.81), moderate to severe calcification (OR: 0.73; 95% CI, 0.66-0.81), moderate to severe proximal tortuosity (OR: 0.67; 95% CI, 0.59-0.75), bifurcation at the distal cap (OR: 0.66; 95% CI, 0.59-0.73), left anterior descending artery CTO (OR [vs right coronary artery]: 1.44; 95% CI, 1.28-1.62) and left circumflex CTO (OR [vs right coronary artery]: 1.22; 95% CI, 1.07-1.40), non-in-stent restenosis lesion (OR: 0.56; 95% CI, 0.49-0.65), and good distal landing zone (OR: 1.18; 95% CI, 1.06-1.32) were independently associated with primary antegrade wiring crossing success | ||
| 520 | |a CONCLUSIONS: The use of antegrade wiring as the initial strategy was high (83.6%) in our registry. We identified several parameters associated with primary antegrade wiring success | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a CTO-PCI | |
| 650 | 4 | |a antegrade wiring | |
| 650 | 4 | |a chronic total occlusion | |
| 650 | 4 | |a percutaneous coronary intervention | |
| 650 | 4 | |a primary antegrade wiring | |
| 700 | 1 | |a Alexandrou, Michaella |e verfasserin |4 aut | |
| 700 | 1 | |a Mutlu, Deniz |e verfasserin |4 aut | |
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| 700 | 1 | |a Poommipanit, Paul |e verfasserin |4 aut | |
| 700 | 1 | |a Khatri, Jaikirshan J |e verfasserin |4 aut | |
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