Gynecological sarcomas, surgical management : primary, metastatic, and recurrent disease

© IGCS and ESGO 2024. No commercial re-use. See rights and permissions. Published by BMJ..

Adult-type gynecological soft tissue and visceral sarcomas are rare tumors, with an estimated incidence of 13% of all sarcomas and 4% of all gynecological malignancies. They most often develop in the uterus (83%), followed by the ovaries (8%), vulva and vagina (5%), and other gynecological organs (2%). The objective of this review is to provide an overview of the current management of gynecological sarcomas, according to international guidelines. The management of gynecological sarcomas should follow the recommendations for the management of soft tissue and visceral sarcomas. Centralizing cases in expert centers improves patient survival, both for the diagnostic phase and for multidisciplinary therapeutic management. In the case of pelvic soft tissue sarcomas, a radiological biopsy is essential before any surgical decision is taken. In the case of a myometrial tumour which may correspond to a sarcoma, if conservative surgery such as myomectomy or morcellation is planned, an ultrasound-guided biopsy with pathological analysis including comparative genomic hybridization analysis must be carried out. In all cases, en bloc surgery, without rupture, is mandatory. Many rare histological subtypes require specific surgical management.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:34

Enthalten in:

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 34(2024), 3 vom: 04. März, Seite 393-402

Sprache:

Englisch

Beteiligte Personen:

Ferron, Gwenael [VerfasserIn]
Bataillon, Guillaume [VerfasserIn]
Martinez, Alejandra [VerfasserIn]
Chibon, Frederic [VerfasserIn]
Valentin, Thibaud [VerfasserIn]

Links:

Volltext

Themen:

Journal Article
Pathology
Pelvis
Review
Sarcoma
Surgical oncology

Anmerkungen:

Date Completed 06.03.2024

Date Revised 06.03.2024

published: Electronic

Citation Status MEDLINE

doi:

10.1136/ijgc-2023-004582

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM369280431