PrEP Discontinuation In A US National Cohort Of Sexual And Gender Minority Populations, 2017-22
In the US, sexual and gender minority populations are disproportionately affected by HIV. Pre-exposure prophylaxis (PrEP) is a key prevention method, but its effectiveness relies on consistent usage. Our four-year national cohort study explored PrEP discontinuation among sexual and gender minority people who initiated PrEP. We found a high annual rate of discontinuation (35-40 percent) after PrEP initiation. Multivariable analysis with 6,410 person-years identified housing instability and prior history of PrEP discontinuation as predictors of discontinuation. Conversely, older age, clinical indication for PrEP, and having health insurance were associated with ongoing PrEP use. To promote sustained PrEP use, strategies should focus on supporting those at high risk for discontinuation, such as younger people, those without stable housing or health insurance, and prior PrEP discontinuers.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2024 |
|---|---|
| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:43 |
|---|---|
| Enthalten in: |
Health affairs (Project Hope) - 43(2024), 3 vom: 12. März, Seite 443-451 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Guo, Yan [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
|---|
| Anmerkungen: |
Date Completed 06.03.2024 Date Revised 06.03.2024 published: Print Citation Status MEDLINE |
|---|
| doi: |
10.1377/hlthaff.2023.00867 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM369274768 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM369274768 | ||
| 003 | DE-627 | ||
| 005 | 20240306233152.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 240305s2024 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1377/hlthaff.2023.00867 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1318.xml |
| 035 | |a (DE-627)NLM369274768 | ||
| 035 | |a (NLM)38437609 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Guo, Yan |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a PrEP Discontinuation In A US National Cohort Of Sexual And Gender Minority Populations, 2017-22 |
| 264 | 1 | |c 2024 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 06.03.2024 | ||
| 500 | |a Date Revised 06.03.2024 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a In the US, sexual and gender minority populations are disproportionately affected by HIV. Pre-exposure prophylaxis (PrEP) is a key prevention method, but its effectiveness relies on consistent usage. Our four-year national cohort study explored PrEP discontinuation among sexual and gender minority people who initiated PrEP. We found a high annual rate of discontinuation (35-40 percent) after PrEP initiation. Multivariable analysis with 6,410 person-years identified housing instability and prior history of PrEP discontinuation as predictors of discontinuation. Conversely, older age, clinical indication for PrEP, and having health insurance were associated with ongoing PrEP use. To promote sustained PrEP use, strategies should focus on supporting those at high risk for discontinuation, such as younger people, those without stable housing or health insurance, and prior PrEP discontinuers | ||
| 650 | 4 | |a Journal Article | |
| 700 | 1 | |a Westmoreland, Drew A |e verfasserin |4 aut | |
| 700 | 1 | |a D'Angelo, Alexa |e verfasserin |4 aut | |
| 700 | 1 | |a Mirzayi, Chloe |e verfasserin |4 aut | |
| 700 | 1 | |a Dearolf, Michelle |e verfasserin |4 aut | |
| 700 | 1 | |a Carneiro, Pedro B |e verfasserin |4 aut | |
| 700 | 1 | |a Ray, Meredith |e verfasserin |4 aut | |
| 700 | 1 | |a Pantalone, David W |e verfasserin |4 aut | |
| 700 | 1 | |a Carrico, Adam W |e verfasserin |4 aut | |
| 700 | 1 | |a Patel, Viraj V |e verfasserin |4 aut | |
| 700 | 1 | |a Golub, Sarit A |e verfasserin |4 aut | |
| 700 | 1 | |a Hirshfield, Sabina |e verfasserin |4 aut | |
| 700 | 1 | |a Hoover, Donald |e verfasserin |4 aut | |
| 700 | 1 | |a Nash, Denis |e verfasserin |4 aut | |
| 700 | 1 | |a Grov, Christian |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Health affairs (Project Hope) |d 1981 |g 43(2024), 3 vom: 12. März, Seite 443-451 |w (DE-627)NLM012834297 |x 1544-5208 |7 nnns |
| 773 | 1 | 8 | |g volume:43 |g year:2024 |g number:3 |g day:12 |g month:03 |g pages:443-451 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1377/hlthaff.2023.00867 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 43 |j 2024 |e 3 |b 12 |c 03 |h 443-451 | ||