Associations between neutrophil-to-lymphocyte/platelet-to-lymphocyte and recovery in sudden sensorineural hearing loss

Aims: This study investigated the nonlinear associations between neutrophil-to-lymphocyte (NLR)/platelet-to-lymphocyte (PLR) and recovery rates in sudden sensorineural hearing loss (SSNHL). Methods: Total of 244 SSNHL patients were included. The primary outcome was recovery rate. Results: A nonlinear association was detected between NLR and recovery rate using the LOWESS method, with a knot of 3. Patients with NLR ≥3 had a higher recovery rate than NLR <3. Using the linear-spline function, NLR was significantly associated with high recovery rate when NLR was <3. However, when NLR was ≥3, this association became nonsignificant. The trend test showed a similar result. PLR was not associated with recovery rate. Conclusion: The association between NLR and recovery rate is nonlinear, with a knot of around three. PLR is not associated with recovery rate.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:18

Enthalten in:

Biomarkers in medicine - 18(2024), 3 vom: 13. Feb., Seite 115-122

Sprache:

Englisch

Beteiligte Personen:

Huang, Xinmei [VerfasserIn]
Ni, Xupei [VerfasserIn]
Shen, Jun [VerfasserIn]
Chen, Lihua [VerfasserIn]
Xu, Liying [VerfasserIn]
Tang, Xuxia [VerfasserIn]

Links:

Volltext

Themen:

Cohort study
Journal Article
Neutrophil-to-lymphocyte ratio
Platelet-to-lymphocyte ratio
Prognosis
Sensorineural hearing loss

Anmerkungen:

Date Completed 15.03.2024

Date Revised 15.03.2024

published: Print-Electronic

Citation Status MEDLINE

doi:

10.2217/bmm-2022-0729

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM369261348