Validity and reliability of the Swedish version of the Leicester Cough Questionnaire in unexplained chronic cough

Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved..

BACKGROUND: Cough is considered chronic when it lasts for >8 weeks. When no medical explanation can be found it is often called unexplained chronic cough (UCC), which may affect health-related quality of life (HRQOL). This study aimed to assesses the validity and reliability of the Swedish version of the Leicester Cough Questionnaire (LCQ-S) in patients with UCC.

METHODS: Seventy-six consecutively selected patients with UCC replied to: a local questionnaire; the LCQ-S; a Visual Analog Scale (VAS) for cough; the Swedish version of the Hull Airway Reflux Questionnaire (HARQ-S); and the Chemical Sensitivity Scale for Sensory Hyperreactivity (CSS-SHR). To evaluate the reproducibility of the LCQ-S, the VAS and LCQ-S were answered again after two to four weeks.

RESULTS: Seventy-four patients (17 men) answered the questionnaires at baseline. Concurrent validity for LCQ-S was regarded as moderate with the VAS for cough and HARQ-S. Internal consistency using Cronbach's alpha was high for the LCQ-S total score (0.92) and satisfactory for the LCQ-S domains (0.78-0.83). Reliability and reproducibility were analysed in 57 patients (14 men). Intra-class correlation for the LCQ-S total score and domains showed strong reliability (≥0.92), without any significant differences over time. The standard error of measurement and the smallest real difference were 1.26 and 3.49, respectively. The Bland-Altman plot showed no systematic change in the mean values.

CONCLUSIONS: The LCQ-S has good validity and reliability and can be used in clinical settings to evaluate HRQOL in Swedish-speaking adult patients with UCC.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:224

Enthalten in:

Respiratory medicine - 224(2024) vom: 28. März, Seite 107582

Sprache:

Englisch

Beteiligte Personen:

Ternesten-Hasséus, Ewa [VerfasserIn]
Johansson, Ewa-Lena [VerfasserIn]

Links:

Volltext

Themen:

Chronic cough
Health-related quality of life questionnaire
Journal Article
Patient-reported outcome
Unexplained chronic cough

Anmerkungen:

Date Completed 18.03.2024

Date Revised 18.03.2024

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1016/j.rmed.2024.107582

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM369183878