Relationship between Static Lung Compliance and Extubation Failure in Postoperative Cardiac Surgery Patients
BACKGROUND: Static lung compliance, which is seriously affected during surgery, can lead to respiratory failure and extubation failure, which is little explored in the decision to extubate after cardiac surgery.
OBJECTIVE: To evaluate static lung compliance in the postoperative period of cardiac surgery and relate its possible reduction to cases of extubation failure in patients submitted to the fast-track method of extubation.
METHODS: Patients undergoing cardiac surgery using cardiopulmonary bypass (CPB) at a state university hospital admitted to the ICU under sedation and residual block were included. Their static lung compliance was assessed on the mechanical ventilator using software that uses least squares fitting (LSF) for measurement. Within 48 hours of extubation, the patients were observed for the need for reintubation due to respiratory failure. The level of significance adopted for the statistical tests was 5%, i.e., p<0.05.
RESULTS: 77 patients (75.49%) achieved successful extubation and 25 (24.51%) failed extubation. Patients who failed extubation had lower static lung compliance compared to those who succeeded (p<0.001). We identified the cut-off point for compliance through analysis of the Receiver Operating Characteristic Curve (ROC), with the cut-off point being compliance <41ml/cmH2O associated with a higher probability of extubation failure (p<0.001). In the multiple regression analysis, the influence of lung compliance (divided by the ROC curve cut-off point) was found to be 9.1 times greater for patients with compliance <41ml/cmH2O (p< 0.003).
CONCLUSIONS: Static lung compliance <41ml/cmH2O is a factor that compromises the success of extubation in the postoperative period of cardiac surgery.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2024 |
|---|---|
| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:121 |
|---|---|
| Enthalten in: |
Arquivos brasileiros de cardiologia - 121(2024), 2 vom: 26., Seite e20230350 |
| Sprache: |
Portugiesisch |
|---|
| Weiterer Titel: |
Relação entre a Complacência Pulmonar Estática e a Falha de Extubação em Pacientes Pós-Operatório de Cirurgia Cardíaca |
|---|
| Beteiligte Personen: |
Ramos, Thais Bento Rudge [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
|---|
| Anmerkungen: |
Date Completed 04.03.2024 Date Revised 04.03.2024 published: Electronic-eCollection Citation Status MEDLINE |
|---|
| doi: |
10.36660/abc.20230350 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM369122046 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM369122046 | ||
| 003 | DE-627 | ||
| 005 | 20240304232709.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 240301s2024 xx |||||o 00| ||por c | ||
| 024 | 7 | |a 10.36660/abc.20230350 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1316.xml |
| 035 | |a (DE-627)NLM369122046 | ||
| 035 | |a (NLM)38422308 | ||
| 035 | |a (PII)S0066-782X2024000200302 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a por | ||
| 100 | 1 | |a Ramos, Thais Bento Rudge |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Relationship between Static Lung Compliance and Extubation Failure in Postoperative Cardiac Surgery Patients |
| 246 | 3 | 3 | |a Relação entre a Complacência Pulmonar Estática e a Falha de Extubação em Pacientes Pós-Operatório de Cirurgia Cardíaca |
| 264 | 1 | |c 2024 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 04.03.2024 | ||
| 500 | |a Date Revised 04.03.2024 | ||
| 500 | |a published: Electronic-eCollection | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a BACKGROUND: Static lung compliance, which is seriously affected during surgery, can lead to respiratory failure and extubation failure, which is little explored in the decision to extubate after cardiac surgery | ||
| 520 | |a OBJECTIVE: To evaluate static lung compliance in the postoperative period of cardiac surgery and relate its possible reduction to cases of extubation failure in patients submitted to the fast-track method of extubation | ||
| 520 | |a METHODS: Patients undergoing cardiac surgery using cardiopulmonary bypass (CPB) at a state university hospital admitted to the ICU under sedation and residual block were included. Their static lung compliance was assessed on the mechanical ventilator using software that uses least squares fitting (LSF) for measurement. Within 48 hours of extubation, the patients were observed for the need for reintubation due to respiratory failure. The level of significance adopted for the statistical tests was 5%, i.e., p<0.05 | ||
| 520 | |a RESULTS: 77 patients (75.49%) achieved successful extubation and 25 (24.51%) failed extubation. Patients who failed extubation had lower static lung compliance compared to those who succeeded (p<0.001). We identified the cut-off point for compliance through analysis of the Receiver Operating Characteristic Curve (ROC), with the cut-off point being compliance <41ml/cmH2O associated with a higher probability of extubation failure (p<0.001). In the multiple regression analysis, the influence of lung compliance (divided by the ROC curve cut-off point) was found to be 9.1 times greater for patients with compliance <41ml/cmH2O (p< 0.003) | ||
| 520 | |a CONCLUSIONS: Static lung compliance <41ml/cmH2O is a factor that compromises the success of extubation in the postoperative period of cardiac surgery | ||
| 650 | 4 | |a Journal Article | |
| 700 | 1 | |a Figueiredo, Luciana Castilho |e verfasserin |4 aut | |
| 700 | 1 | |a Martins, Luiz Claudio |e verfasserin |4 aut | |
| 700 | 1 | |a Falcão, Antonio Luis Eiras |e verfasserin |4 aut | |
| 700 | 1 | |a Ratti, Lígia Dos Santos Roceto |e verfasserin |4 aut | |
| 700 | 1 | |a Petrucci, Orlando |e verfasserin |4 aut | |
| 700 | 1 | |a Dragosavac, Desanka |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Arquivos brasileiros de cardiologia |d 1950 |g 121(2024), 2 vom: 26., Seite e20230350 |w (DE-627)NLM000272981 |x 1678-4170 |7 nnns |
| 773 | 1 | 8 | |g volume:121 |g year:2024 |g number:2 |g day:26 |g pages:e20230350 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.36660/abc.20230350 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 121 |j 2024 |e 2 |b 26 |h e20230350 | ||