Very-early detection of atrial fibrillation after ablation evaluated by a wearable ECG-patch predicts late blanking period recurrence : Preliminary data from a prospective registry
© 2024 The Authors. Published by Elsevier B.V..
Introduction: Atrial fibrillation (AF) ablation represents a safe and effective procedure to restore sinus rhythm. The idea that post-procedural AF episodes - during the blanking period - are not considered treatment failure has been increasingly challenged. The E-Patch, a single-use adhesive electrode, facilitates extended continuous ECG monitoring for 120 h. This pilot study aims to assess the effectiveness of this ambulatory monitoring device and investigate whether very-early AF recurrence correlates with delayed blanking period ablation outcomes.
Methods: We conducted a single-center, prospective, longitudinal study, including consecutive post-ablation patients monitored with the E-patch. The ability of the device to continuously record was analyzed, as well as the occurrence of AF episodes during external 7-day loop-recorder in the 2nd-month post-ablation.
Results: We included 40 patients, median age 62 years (IQR 56-70). E-Patch monitoring was obtained for a median of 118 h (IQR 112-120), with no discomfort nor interpretation artefacts. Very-early AF recurrence was detected in 11 (27.5 %) patients, with a median AF burden of 7 % (IQR 6 %-33 %). Late-blanking period AF was detected in 13 (33 %) of the external 7-day loop recordings. Of the 11 patients that had very-early AF recurrence, 10 (91 %) had late-blanking AF. Very-early AF detection showed 77 % (95 % CI 64 %-90 %) sensitivity and 96 % (95 % CI 90-100 %) specificity in predicting late-blanking AF, with a non-parametric ROC curve AUC of 0.903 (95 % 0.797--1.0).
Conclusion: The E-Patch was able to detect very-early AF during an extended period. Very-early AF detection emerges as a predictor of AF recurrence during the late blanking period post-ablation.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:51 |
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| Enthalten in: |
International journal of cardiology. Heart & vasculature - 51(2024) vom: 30. März, Seite 101369 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Marques Antunes, Miguel [VerfasserIn] |
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| Links: |
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| Themen: |
Ablation |
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| Anmerkungen: |
Date Revised 01.03.2024 published: Electronic-eCollection Citation Status PubMed-not-MEDLINE |
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| doi: |
10.1016/j.ijcha.2024.101369 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM36910434X |
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| 100 | 1 | |a Marques Antunes, Miguel |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Very-early detection of atrial fibrillation after ablation evaluated by a wearable ECG-patch predicts late blanking period recurrence |b Preliminary data from a prospective registry |
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| 520 | |a © 2024 The Authors. Published by Elsevier B.V. | ||
| 520 | |a Introduction: Atrial fibrillation (AF) ablation represents a safe and effective procedure to restore sinus rhythm. The idea that post-procedural AF episodes - during the blanking period - are not considered treatment failure has been increasingly challenged. The E-Patch, a single-use adhesive electrode, facilitates extended continuous ECG monitoring for 120 h. This pilot study aims to assess the effectiveness of this ambulatory monitoring device and investigate whether very-early AF recurrence correlates with delayed blanking period ablation outcomes | ||
| 520 | |a Methods: We conducted a single-center, prospective, longitudinal study, including consecutive post-ablation patients monitored with the E-patch. The ability of the device to continuously record was analyzed, as well as the occurrence of AF episodes during external 7-day loop-recorder in the 2nd-month post-ablation | ||
| 520 | |a Results: We included 40 patients, median age 62 years (IQR 56-70). E-Patch monitoring was obtained for a median of 118 h (IQR 112-120), with no discomfort nor interpretation artefacts. Very-early AF recurrence was detected in 11 (27.5 %) patients, with a median AF burden of 7 % (IQR 6 %-33 %). Late-blanking period AF was detected in 13 (33 %) of the external 7-day loop recordings. Of the 11 patients that had very-early AF recurrence, 10 (91 %) had late-blanking AF. Very-early AF detection showed 77 % (95 % CI 64 %-90 %) sensitivity and 96 % (95 % CI 90-100 %) specificity in predicting late-blanking AF, with a non-parametric ROC curve AUC of 0.903 (95 % 0.797--1.0) | ||
| 520 | |a Conclusion: The E-Patch was able to detect very-early AF during an extended period. Very-early AF detection emerges as a predictor of AF recurrence during the late blanking period post-ablation | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Ablation | |
| 650 | 4 | |a Arrythmia | |
| 650 | 4 | |a Atrial fibrillation | |
| 650 | 4 | |a Blanking period | |
| 650 | 4 | |a External loop recorder | |
| 650 | 4 | |a Recurrence | |
| 700 | 1 | |a Silva Cunha, Pedro |e verfasserin |4 aut | |
| 700 | 1 | |a Lacerda Teixeira, Bárbara |e verfasserin |4 aut | |
| 700 | 1 | |a Portugal, Guilherme |e verfasserin |4 aut | |
| 700 | 1 | |a Valente, Bruno |e verfasserin |4 aut | |
| 700 | 1 | |a Lousinha, Ana |e verfasserin |4 aut | |
| 700 | 1 | |a Delgado, Ana Sofia |e verfasserin |4 aut | |
| 700 | 1 | |a Alves, Sandra |e verfasserin |4 aut | |
| 700 | 1 | |a Guerra, Cátia |e verfasserin |4 aut | |
| 700 | 1 | |a Cruz Ferreira, Rui |e verfasserin |4 aut | |
| 700 | 1 | |a Martins Oliveira, Mário |e verfasserin |4 aut | |
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