Long-term outcomes of children after prenatal exposure to maternal cancer and its treatment

© 2024 The Authors. Acta Obstetricia et Gynecologica Scandinavica published by John Wiley & Sons Ltd on behalf of Nordic Federation of Societies of Obstetrics and Gynecology (NFOG)..

The incidence of antenatal cancer is increasing, prompting a medical-ethical evaluation. The International Network on Cancer, Infertility, and Pregnancy (INCIP) was established to study cancer treatment safety during pregnancy and its impact on maternal and child health. Pivotal research has led to a paradigm shift in clinical management, demonstrating the feasibility and safety of most antenatal oncological treatments. Short-term outcomes reveal normal growth and cardiac function in the exposed offspring, but caution is advised against first-trimester chemotherapy. Psychological impact studies highlight the elevated levels of distress in pregnant cancer patients, underscoring the need for personalized information and ongoing psychological support. Long-term follow-up studies address gaps in postnatal impacts, while research into specific chemotherapeutic agents continues. Despite generally reassuring outcomes, continued monitoring is crucial, especially in families, such as those where the child was born premature after cancer (treatment) during pregnancy or where mothers are frequently absent due to continued illness or have died from. The ongoing INCIP child follow-up initiative aims to further elucidate knowledge gaps, emphasizing the importance of large-scale studies and personalized patient care.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:103

Enthalten in:

Acta obstetricia et gynecologica Scandinavica - 103(2024), 4 vom: 26. Apr., Seite 757-760

Sprache:

Englisch

Beteiligte Personen:

Huis In 't Veld, Evangeline A [VerfasserIn]
Van Assche, Indra A [VerfasserIn]
Amant, Frederic [VerfasserIn]

Links:

Volltext

Themen:

Antenatal cancer
Counseling
Follow‐up
Health
Impact
Journal Article
Neurocognition
Offspring

Anmerkungen:

Date Completed 05.04.2024

Date Revised 06.04.2024

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1111/aogs.14811

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM369090500