Dispersion patterns of SARS-CoV-2 variants Gamma, Lambda and Mu in Latin America and the Caribbean
© 2024. The Author(s)..
Latin America and Caribbean (LAC) regions were an important epicenter of the COVID-19 pandemic and SARS-CoV-2 evolution. Through the COVID-19 Genomic Surveillance Regional Network (COVIGEN), LAC countries produced an important number of genomic sequencing data that made possible an enhanced SARS-CoV-2 genomic surveillance capacity in the Americas, paving the way for characterization of emerging variants and helping to guide the public health response. In this study we analyzed approximately 300,000 SARS-CoV-2 sequences generated between February 2020 and March 2022 by multiple genomic surveillance efforts in LAC and reconstructed the diffusion patterns of the main variants of concern (VOCs) and of interest (VOIs) possibly originated in the Region. Our phylogenetic analysis revealed that the spread of variants Gamma, Lambda and Mu reflects human mobility patterns due to variations of international air passenger transportation and gradual lifting of social distance measures previously implemented in countries. Our results highlight the potential of genetic data to reconstruct viral spread and unveil preferential routes of viral migrations that are shaped by human mobility patterns.
Medienart: |
E-Artikel |
---|
Erscheinungsjahr: |
2024 |
---|---|
Erschienen: |
2024 |
Enthalten in: |
Zur Gesamtaufnahme - volume:15 |
---|---|
Enthalten in: |
Nature communications - 15(2024), 1 vom: 28. Feb., Seite 1837 |
Sprache: |
Englisch |
---|
Links: |
---|
Themen: |
---|
Anmerkungen: |
Date Completed 01.03.2024 Date Revised 02.03.2024 published: Electronic Citation Status MEDLINE |
---|
doi: |
10.1038/s41467-024-46143-9 |
---|
funding: |
|
---|---|
Förderinstitution / Projekttitel: |
|
PPN (Katalog-ID): |
NLM369087356 |
---|
LEADER | 01000caa a22002652 4500 | ||
---|---|---|---|
001 | NLM369087356 | ||
003 | DE-627 | ||
005 | 20240302232642.0 | ||
007 | cr uuu---uuuuu | ||
008 | 240229s2024 xx |||||o 00| ||eng c | ||
024 | 7 | |a 10.1038/s41467-024-46143-9 |2 doi | |
028 | 5 | 2 | |a pubmed24n1314.xml |
035 | |a (DE-627)NLM369087356 | ||
035 | |a (NLM)38418815 | ||
040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
041 | |a eng | ||
100 | 1 | |a Gräf, Tiago |e verfasserin |4 aut | |
245 | 1 | 0 | |a Dispersion patterns of SARS-CoV-2 variants Gamma, Lambda and Mu in Latin America and the Caribbean |
264 | 1 | |c 2024 | |
336 | |a Text |b txt |2 rdacontent | ||
337 | |a ƒaComputermedien |b c |2 rdamedia | ||
338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
500 | |a Date Completed 01.03.2024 | ||
500 | |a Date Revised 02.03.2024 | ||
500 | |a published: Electronic | ||
500 | |a Citation Status MEDLINE | ||
520 | |a © 2024. The Author(s). | ||
520 | |a Latin America and Caribbean (LAC) regions were an important epicenter of the COVID-19 pandemic and SARS-CoV-2 evolution. Through the COVID-19 Genomic Surveillance Regional Network (COVIGEN), LAC countries produced an important number of genomic sequencing data that made possible an enhanced SARS-CoV-2 genomic surveillance capacity in the Americas, paving the way for characterization of emerging variants and helping to guide the public health response. In this study we analyzed approximately 300,000 SARS-CoV-2 sequences generated between February 2020 and March 2022 by multiple genomic surveillance efforts in LAC and reconstructed the diffusion patterns of the main variants of concern (VOCs) and of interest (VOIs) possibly originated in the Region. Our phylogenetic analysis revealed that the spread of variants Gamma, Lambda and Mu reflects human mobility patterns due to variations of international air passenger transportation and gradual lifting of social distance measures previously implemented in countries. Our results highlight the potential of genetic data to reconstruct viral spread and unveil preferential routes of viral migrations that are shaped by human mobility patterns | ||
650 | 4 | |a Journal Article | |
700 | 1 | |a Martinez, Alexander A |e verfasserin |4 aut | |
700 | 1 | |a Bello, Gonzalo |e verfasserin |4 aut | |
700 | 1 | |a Dellicour, Simon |e verfasserin |4 aut | |
700 | 1 | |a Lemey, Philippe |e verfasserin |4 aut | |
700 | 1 | |a Colizza, Vittoria |e verfasserin |4 aut | |
700 | 1 | |a Mazzoli, Mattia |e verfasserin |4 aut | |
700 | 1 | |a Poletto, Chiara |e verfasserin |4 aut | |
700 | 1 | |a Cardoso, Vanessa Leiko Oikawa |e verfasserin |4 aut | |
700 | 1 | |a da Silva, Alexandre Freitas |e verfasserin |4 aut | |
700 | 0 | |a COVIGEN |e verfasserin |4 aut | |
700 | 1 | |a Motta, Fernando Couto |e verfasserin |4 aut | |
700 | 1 | |a Resende, Paola Cristina |e verfasserin |4 aut | |
700 | 1 | |a Siqueira, Marilda M |e verfasserin |4 aut | |
700 | 1 | |a Franco, Leticia |e verfasserin |4 aut | |
700 | 1 | |a Gresh, Lionel |e verfasserin |4 aut | |
700 | 1 | |a Gabastou, Jean-Marc |e verfasserin |4 aut | |
700 | 1 | |a Rodriguez, Angel |e verfasserin |4 aut | |
700 | 1 | |a Vicari, Andrea |e verfasserin |4 aut | |
700 | 1 | |a Aldighieri, Sylvain |e verfasserin |4 aut | |
700 | 1 | |a Mendez-Rico, Jairo |e verfasserin |4 aut | |
700 | 1 | |a Leite, Juliana Almeida |e verfasserin |4 aut | |
700 | 1 | |a Baumeister, Elsa |e investigator |4 oth | |
700 | 1 | |a Campos, Josefina |e investigator |4 oth | |
700 | 1 | |a Pontoriero, Andrea |e investigator |4 oth | |
700 | 1 | |a Martin, Indira |e investigator |4 oth | |
700 | 1 | |a Ferguson, Kirvina |e investigator |4 oth | |
700 | 1 | |a Johnson, Draven |e investigator |4 oth | |
700 | 1 | |a Beckles, Songee |e investigator |4 oth | |
700 | 1 | |a Forde, Kasandra |e investigator |4 oth | |
700 | 1 | |a Sosa, Aldo |e investigator |4 oth | |
700 | 1 | |a Melendez, Roberto |e investigator |4 oth | |
700 | 1 | |a Loayza, Roxana |e investigator |4 oth | |
700 | 1 | |a Avila, Cinthia |e investigator |4 oth | |
700 | 1 | |a Fernández, Evelin Esther Fortun |e investigator |4 oth | |
700 | 1 | |a Otazo, Carol Jessica Guzman |e investigator |4 oth | |
700 | 1 | |a Siqueira, Marilda Mendonça |e investigator |4 oth | |
700 | 1 | |a Motta, Fernando Couto |e investigator |4 oth | |
700 | 1 | |a de Oliveira Santos, Katia Corrêa |e investigator |4 oth | |
700 | 1 | |a Abbud, Adriano |e investigator |4 oth | |
700 | 1 | |a Dos Santos, Mirleide Cordeiro |e investigator |4 oth | |
700 | 1 | |a de Almeida Ferreira, Jessylene |e investigator |4 oth | |
700 | 1 | |a Fasce, Rodrigo |e investigator |4 oth | |
700 | 1 | |a Fernandes, Jorge |e investigator |4 oth | |
700 | 1 | |a Rangel, Sergio Gómez |e investigator |4 oth | |
700 | 1 | |a Mercado, Marcela Maria |e investigator |4 oth | |
700 | 1 | |a Pelaez, Dioselina |e investigator |4 oth | |
700 | 1 | |a Soto-Garita, Claudio |e investigator |4 oth | |
700 | 1 | |a Cordero-Laurent, Estela |e investigator |4 oth | |
700 | 1 | |a Duarte-Martínez, Francisco |e investigator |4 oth | |
700 | 1 | |a Brenes, Hebleen |e investigator |4 oth | |
700 | 1 | |a Sanchez, Isaac Miguel |e investigator |4 oth | |
700 | 1 | |a Imbert, Yvonne |e investigator |4 oth | |
700 | 1 | |a Caicedo, Alfredo Bruno |e investigator |4 oth | |
700 | 1 | |a de Mora Coloma, Domenica Joseth |e investigator |4 oth | |
700 | 1 | |a López, Dalia Xochitl Sandoval |e investigator |4 oth | |
700 | 1 | |a Alvarado, Denis Gerson Jovel |e investigator |4 oth | |
700 | 1 | |a Morán, Deny Lisset Martínez |e investigator |4 oth | |
700 | 1 | |a Pacheco, Claudia |e investigator |4 oth | |
700 | 1 | |a Mendoza, Linda |e investigator |4 oth | |
700 | 1 | |a Whyte-Chin, Joyce |e investigator |4 oth | |
700 | 1 | |a Abdul-Kadir, Mustapha |e investigator |4 oth | |
700 | 1 | |a Boncy, Jacques |e investigator |4 oth | |
700 | 1 | |a Journel, Ito |e investigator |4 oth | |
700 | 1 | |a Paz, Mitzi Castro |e investigator |4 oth | |
700 | 1 | |a Alvarado, Sofia Carolina |e investigator |4 oth | |
700 | 1 | |a Avilez, Soany |e investigator |4 oth | |
700 | 1 | |a Brown, Michelle |e investigator |4 oth | |
700 | 1 | |a Arambula, Caludia Elena Wong |e investigator |4 oth | |
700 | 1 | |a González, Ernesto Ramírez |e investigator |4 oth | |
700 | 1 | |a Martinez, Alexander A |e investigator |4 oth | |
700 | 1 | |a Gonzalez, Claudia M |e investigator |4 oth | |
700 | 1 | |a Moreno Arevalo, Brechla |e investigator |4 oth | |
700 | 1 | |a Franco, Danilo |e investigator |4 oth | |
700 | 1 | |a Lopez-Verges, Sandra |e investigator |4 oth | |
700 | 1 | |a Pascale, Juan Miguel |e investigator |4 oth | |
700 | 1 | |a Vazquez, Cynthia |e investigator |4 oth | |
700 | 1 | |a Gonzalez, Sandra |e investigator |4 oth | |
700 | 1 | |a Serrano, Nancy Rojas |e investigator |4 oth | |
700 | 1 | |a Rojas, Carlos Patricio Padilla |e investigator |4 oth | |
700 | 1 | |a Pinas, Phyllis |e investigator |4 oth | |
700 | 1 | |a Asebeh, Navienda |e investigator |4 oth | |
700 | 1 | |a Carrington, Christine V F |e investigator |4 oth | |
700 | 1 | |a Sahadeo, Nikita S D |e investigator |4 oth | |
700 | 1 | |a Chiparelli, Hector |e investigator |4 oth | |
700 | 1 | |a Goñi, Natalia |e investigator |4 oth | |
700 | 1 | |a Rodriguez, Lieska |e investigator |4 oth | |
700 | 1 | |a D'Angelo, Pierina |e investigator |4 oth | |
773 | 0 | 8 | |i Enthalten in |t Nature communications |d 2010 |g 15(2024), 1 vom: 28. Feb., Seite 1837 |w (DE-627)NLM199274525 |x 2041-1723 |7 nnns |
773 | 1 | 8 | |g volume:15 |g year:2024 |g number:1 |g day:28 |g month:02 |g pages:1837 |
856 | 4 | 0 | |u http://dx.doi.org/10.1038/s41467-024-46143-9 |3 Volltext |
912 | |a GBV_USEFLAG_A | ||
912 | |a GBV_NLM | ||
951 | |a AR | ||
952 | |d 15 |j 2024 |e 1 |b 28 |c 02 |h 1837 |