Profile of patients hospitalized in intensive cardiac care units in France : ADDICT-ICCU registry
Copyright © 2024. Published by Elsevier Masson SAS..
BACKGROUND: Intensive cardiac care units (ICCU) were initially developed to monitor ventricular arrhythmias after myocardial infarction. In recent decades, ICCU have diversified their activities.
AIM: To determine the type of patients hospitalized in ICCU in France.
METHODS: We analysed the characteristics of patients enrolled in the ADDICT-ICCU registry (NCT05063097), a prospective study of consecutive patients admitted to ICCU in 39 centres throughout France from 7th-22nd April 2021. In-hospital major adverse events (MAE) (death, resuscitated cardiac arrest and cardiogenic shock) were recorded.
RESULTS: Among 1499 patients (median age 65 [interquartile range 54-74] years, 69.6% male, 21.7% diabetes mellitus, 64.7% current or previous smokers), 34.9% had a history of coronary artery disease, 11.7% atrial fibrillation and 5.2% cardiomyopathy. The most frequent reason for admission to ICCU was acute coronary syndromes (ACS; 51.5%), acute heart failure (AHF; 14.1%) and unexplained chest pain (6.8%). An invasive procedure was performed in 36.2%. "Advanced" ICCU therapies were required for 19.9% of patients (intravenous diuretics 18.4%, non-invasive ventilation 6.1%, inotropic drugs 2.3%). No invasive procedures or advanced therapies were required in 44.1%. Cardiac computed tomography or magnetic resonance imaging was carried out in 12.3% of patients. The median length of ICCU hospitalization was 2.0 (interquartile range 1.0-4.0) days. The mean rate of MAE was 4.5%, and was highest in patients with AHF (10.4%).
CONCLUSIONS: ACS remains the main cause of admissions to ICCU, with most having a low rate of in-hospital MAE. Most patients experience a brief stay in ICCU before being discharged home. AHF is associated with highest death rate and with higher resource consumption.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:117 |
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| Enthalten in: |
Archives of cardiovascular diseases - 117(2024), 3 vom: 25. März, Seite 195-203 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Gall, Emmanuel [VerfasserIn] |
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| Links: |
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| Themen: |
Cardiovascular disease |
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| Anmerkungen: |
Date Completed 25.03.2024 Date Revised 25.03.2024 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.acvd.2023.12.009 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM369082249 |
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| 100 | 1 | |a Gall, Emmanuel |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Profile of patients hospitalized in intensive cardiac care units in France |b ADDICT-ICCU registry |
| 264 | 1 | |c 2024 | |
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| 500 | |a Date Completed 25.03.2024 | ||
| 500 | |a Date Revised 25.03.2024 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2024. Published by Elsevier Masson SAS. | ||
| 520 | |a BACKGROUND: Intensive cardiac care units (ICCU) were initially developed to monitor ventricular arrhythmias after myocardial infarction. In recent decades, ICCU have diversified their activities | ||
| 520 | |a AIM: To determine the type of patients hospitalized in ICCU in France | ||
| 520 | |a METHODS: We analysed the characteristics of patients enrolled in the ADDICT-ICCU registry (NCT05063097), a prospective study of consecutive patients admitted to ICCU in 39 centres throughout France from 7th-22nd April 2021. In-hospital major adverse events (MAE) (death, resuscitated cardiac arrest and cardiogenic shock) were recorded | ||
| 520 | |a RESULTS: Among 1499 patients (median age 65 [interquartile range 54-74] years, 69.6% male, 21.7% diabetes mellitus, 64.7% current or previous smokers), 34.9% had a history of coronary artery disease, 11.7% atrial fibrillation and 5.2% cardiomyopathy. The most frequent reason for admission to ICCU was acute coronary syndromes (ACS; 51.5%), acute heart failure (AHF; 14.1%) and unexplained chest pain (6.8%). An invasive procedure was performed in 36.2%. "Advanced" ICCU therapies were required for 19.9% of patients (intravenous diuretics 18.4%, non-invasive ventilation 6.1%, inotropic drugs 2.3%). No invasive procedures or advanced therapies were required in 44.1%. Cardiac computed tomography or magnetic resonance imaging was carried out in 12.3% of patients. The median length of ICCU hospitalization was 2.0 (interquartile range 1.0-4.0) days. The mean rate of MAE was 4.5%, and was highest in patients with AHF (10.4%) | ||
| 520 | |a CONCLUSIONS: ACS remains the main cause of admissions to ICCU, with most having a low rate of in-hospital MAE. Most patients experience a brief stay in ICCU before being discharged home. AHF is associated with highest death rate and with higher resource consumption | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Cardiovascular disease | |
| 650 | 4 | |a Epidemiology | |
| 650 | 4 | |a In-hospital major adverse outcomes | |
| 650 | 4 | |a Intensive cardiac care unit | |
| 650 | 4 | |a Management | |
| 700 | 1 | |a Pezel, Théo |e verfasserin |4 aut | |
| 700 | 1 | |a Lattuca, Benoît |e verfasserin |4 aut | |
| 700 | 1 | |a Hamzi, Kenza |e verfasserin |4 aut | |
| 700 | 1 | |a Puymirat, Etienne |e verfasserin |4 aut | |
| 700 | 1 | |a Piliero, Nicolas |e verfasserin |4 aut | |
| 700 | 1 | |a Deney, Antoine |e verfasserin |4 aut | |
| 700 | 1 | |a Fauvel, Charles |e verfasserin |4 aut | |
| 700 | 1 | |a Aboyans, Victor |e verfasserin |4 aut | |
| 700 | 1 | |a Schurtz, Guillaume |e verfasserin |4 aut | |
| 700 | 1 | |a Bouleti, Claire |e verfasserin |4 aut | |
| 700 | 1 | |a Fabre, Julien |e verfasserin |4 aut | |
| 700 | 1 | |a El Ouahidi, Amine |e verfasserin |4 aut | |
| 700 | 1 | |a Thuaire, Christophe |e verfasserin |4 aut | |
| 700 | 1 | |a Millischer, Damien |e verfasserin |4 aut | |
| 700 | 1 | |a Noirclerc, Nathalie |e verfasserin |4 aut | |
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| 700 | 1 | |a Roubille, François |e verfasserin |4 aut | |
| 700 | 1 | |a Dillinger, Jean-Guillaume |e verfasserin |4 aut | |
| 700 | 1 | |a Henry, Patrick |e verfasserin |4 aut | |
| 700 | 0 | |a ADDICT-ICCU Investigators |e verfasserin |4 aut | |
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