Assessment of the risk of malignancy in Bethesda III thyroid nodules : a comprehensive review

© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature..

The increasing prevalence of thyroid cancer emphasizes the need for a thorough assessment of risk of malignancy in Bethesda III nodules. Various methods ranging commercial platforms of molecular genetic testing (including Afirma® GEC, Afirma® GSC, ThyroSeq® V3, RosettaGX®, ThyGeNEXT®/ThyraMIR®, ThyroidPRINT®) to radionuclide scans and ultrasonography have been investigated to provide a more nuanced comprehension of risk estimation. The integration of molecular studies and imaging techniques into clinical practice may provide clinicians with improved and personalized risk assessment. This integrated approach we feel may enable clinicians to carefully tailor interventions, thereby minimizing the likelihood of unnecessary thyroid surgeries and overall crafting the optimal treatment. By aligning with the evolving landscape of personalized healthcare, this comprehensive strategy ensures a patient-centric approach to thyroid nodule and thyroid cancer management.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - year:2024

Enthalten in:

Endocrine - (2024) vom: 28. Feb.

Sprache:

Englisch

Beteiligte Personen:

Rao, Karthik Nagaraja [VerfasserIn]
Randolph, Gregory W [VerfasserIn]
Lopez, Fernando [VerfasserIn]
Zafereo, Mark [VerfasserIn]
Coca-Pelaz, Andrés [VerfasserIn]
Piazza, Cesare [VerfasserIn]
Dange, Prajwal [VerfasserIn]
Rodrigo, Juan Pablo [VerfasserIn]
Stenman, Göran [VerfasserIn]
de Keizer, Bart [VerfasserIn]
Nixon, Iain [VerfasserIn]
Sinha, Shriyash [VerfasserIn]
Leboulleux, Sophie [VerfasserIn]
Mäkitie, Antti A [VerfasserIn]
Agaimy, Abbas [VerfasserIn]
Thompson, Lester [VerfasserIn]
Ferlito, Alfio [VerfasserIn]
This paper was written by members and invitees of the International Head and Neck Scientific Group [VerfasserIn]

Links:

Volltext

Themen:

Artificial intelligence
Bethesda system
Journal Article
Molecular testing
Review
Risk assessment
Thyroid neoplasms

Anmerkungen:

Date Revised 28.02.2024

published: Print-Electronic

Citation Status Publisher

doi:

10.1007/s12020-024-03737-z

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM369063007