ANCA-associated vasculitis presenting with isolated neurological manifestations in a patient with cocaine abuse : a case report and literature review
© 2024. The Author(s), under exclusive licence to International League of Associations for Rheumatology (ILAR)..
Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a group of rare conditions predominantly affecting small vessels of skin, musculoskeletal, pulmonary, renal, and rarely central and peripheral nervous systems. Isolated neurological manifestations of AAV are uncommon and challenging to diagnose. Cocaine has been reported as a potential trigger for the development of AAV. There are only a few case reports of isolated neurological involvement in cocaine-induced AAV with poorly characterized histopathological features. We present a unique case of AAV with isolated neurological manifestations presenting with multiple cranial neuropathies, leptomeningeal enhancement on imaging and histopathologic evidence of small-vessel vasculitis in the leptomeninges and brain and extensive dural fibrosis in a patient with cocaine abuse. The patient's progressive neurological deficits were controlled after starting immunosuppression with rituximab and prednisone. We also reviewed the literature to provide the diagnostic overview of AAV and evaluate intervention options. To our knowledge, this is the first case of AAV with isolated neurological manifestations and histopathologic evidence of small-vessel vasculitis in a patient with cocaine abuse. Patients with multiple cranial neuropathies and meningeal involvement should be screened for AAV, especially if they have a history of cocaine abuse.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2024 |
|---|---|
| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:43 |
|---|---|
| Enthalten in: |
Clinical rheumatology - 43(2024), 4 vom: 12. Apr., Seite 1401-1407 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Aseem, Fazila [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Antineutrophil cytoplasmic antibody-associated vasculitis |
|---|
| Anmerkungen: |
Date Completed 19.03.2024 Date Revised 15.04.2024 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1007/s10067-024-06919-2 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM369062280 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM369062280 | ||
| 003 | DE-627 | ||
| 005 | 20240415233304.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 240229s2024 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1007/s10067-024-06919-2 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1376.xml |
| 035 | |a (DE-627)NLM369062280 | ||
| 035 | |a (NLM)38416306 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Aseem, Fazila |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a ANCA-associated vasculitis presenting with isolated neurological manifestations in a patient with cocaine abuse |b a case report and literature review |
| 264 | 1 | |c 2024 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 19.03.2024 | ||
| 500 | |a Date Revised 15.04.2024 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2024. The Author(s), under exclusive licence to International League of Associations for Rheumatology (ILAR). | ||
| 520 | |a Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a group of rare conditions predominantly affecting small vessels of skin, musculoskeletal, pulmonary, renal, and rarely central and peripheral nervous systems. Isolated neurological manifestations of AAV are uncommon and challenging to diagnose. Cocaine has been reported as a potential trigger for the development of AAV. There are only a few case reports of isolated neurological involvement in cocaine-induced AAV with poorly characterized histopathological features. We present a unique case of AAV with isolated neurological manifestations presenting with multiple cranial neuropathies, leptomeningeal enhancement on imaging and histopathologic evidence of small-vessel vasculitis in the leptomeninges and brain and extensive dural fibrosis in a patient with cocaine abuse. The patient's progressive neurological deficits were controlled after starting immunosuppression with rituximab and prednisone. We also reviewed the literature to provide the diagnostic overview of AAV and evaluate intervention options. To our knowledge, this is the first case of AAV with isolated neurological manifestations and histopathologic evidence of small-vessel vasculitis in a patient with cocaine abuse. Patients with multiple cranial neuropathies and meningeal involvement should be screened for AAV, especially if they have a history of cocaine abuse | ||
| 650 | 4 | |a Case Reports | |
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Review | |
| 650 | 4 | |a Antineutrophil cytoplasmic antibody-associated vasculitis | |
| 650 | 4 | |a Central nervous system | |
| 650 | 4 | |a Cocaine abuse | |
| 650 | 4 | |a Multiple cranial neuropathy | |
| 650 | 7 | |a Cocaine |2 NLM | |
| 650 | 7 | |a I5Y540LHVR |2 NLM | |
| 700 | 1 | |a Lin, Victor |e verfasserin |4 aut | |
| 700 | 1 | |a Gilbert, Abigail L |e verfasserin |4 aut | |
| 700 | 1 | |a Rivadeneira, Alfredo C |e verfasserin |4 aut | |
| 700 | 1 | |a Jennette, J Charles |e verfasserin |4 aut | |
| 700 | 1 | |a Bouldin, Thomas W |e verfasserin |4 aut | |
| 700 | 1 | |a Khoshbakht, Freshta |e verfasserin |4 aut | |
| 700 | 1 | |a Lee, Yueh Z |e verfasserin |4 aut | |
| 700 | 1 | |a Chamberlin, Kelly |e verfasserin |4 aut | |
| 700 | 1 | |a Gelinne, Aaron |e verfasserin |4 aut | |
| 700 | 1 | |a Mehrabyan, Anahit C |e verfasserin |4 aut | |
| 700 | 1 | |a Javed, Bushra |e verfasserin |4 aut | |
| 700 | 1 | |a Dujmovic Basuroski, Irena |e verfasserin |4 aut | |
| 700 | 1 | |a Diaz, Monica M |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Clinical rheumatology |d 1987 |g 43(2024), 4 vom: 12. Apr., Seite 1401-1407 |w (DE-627)NLM012613037 |x 1434-9949 |7 nnns |
| 773 | 1 | 8 | |g volume:43 |g year:2024 |g number:4 |g day:12 |g month:04 |g pages:1401-1407 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1007/s10067-024-06919-2 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 43 |j 2024 |e 4 |b 12 |c 04 |h 1401-1407 | ||