Hyperdense sign as a predictor for successful recanalization and clinical outcome in acute ischemic stroke : A systematic review and meta-analysis
OBJECTIVE: To assess the prognostic values of hyperdense sign on pretreatment non-contrast head CT scan for successful recanalization (mTICI ≥2b) and 90-day good functional outcome (mRs 0-2) in patients with acute ischemic stroke undergoing mechanical thrombectomy (MT).
METHODS: Literature search on PubMed, EMBASE, and Cochrane databases from inception up to 1 November 2023 was conducted. Twelve studies which reported hyperdense sign, recanalization and clinical outcomes were included in qualitative synthesis and meta-analysis.
RESULTS: Pooled analysis demonstrated a statistically significant association between successful recanalization and hyperdense sign-positive patients who underwent MT (odd ratios (OR) = 1.47, 95% confidence interval (CI) = 1.03-2.10, p = 0.04). No statistically significant association was demonstrated between presence of hyperdense sign and good functional outcome (OR = 1.04, 95% CI: 0.72-1.49, p = 0.85) or symptomatic intracranial hemorrhage sICH (OR: 1.80, 95% CI 0.72-4.47, p = 0.21).
CONCLUSIONS: This meta-analysis demonstrated that pre-intervention hyperdense sign on CT imaging might be useful in prediction of successful recanalization after MT.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - year:2024 |
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| Enthalten in: |
Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences - (2024) vom: 28. Feb., Seite 15910199241235431 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Gharaibeh, Khaled [VerfasserIn] |
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| Links: |
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| Themen: |
Hyperdesne vessel sign |
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| Anmerkungen: |
Date Revised 28.02.2024 published: Print-Electronic Citation Status Publisher |
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| doi: |
10.1177/15910199241235431 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM369052307 |
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| 100 | 1 | |a Gharaibeh, Khaled |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Hyperdense sign as a predictor for successful recanalization and clinical outcome in acute ischemic stroke |b A systematic review and meta-analysis |
| 264 | 1 | |c 2024 | |
| 336 | |a Text |b txt |2 rdacontent | ||
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| 500 | |a Date Revised 28.02.2024 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status Publisher | ||
| 520 | |a OBJECTIVE: To assess the prognostic values of hyperdense sign on pretreatment non-contrast head CT scan for successful recanalization (mTICI ≥2b) and 90-day good functional outcome (mRs 0-2) in patients with acute ischemic stroke undergoing mechanical thrombectomy (MT) | ||
| 520 | |a METHODS: Literature search on PubMed, EMBASE, and Cochrane databases from inception up to 1 November 2023 was conducted. Twelve studies which reported hyperdense sign, recanalization and clinical outcomes were included in qualitative synthesis and meta-analysis | ||
| 520 | |a RESULTS: Pooled analysis demonstrated a statistically significant association between successful recanalization and hyperdense sign-positive patients who underwent MT (odd ratios (OR) = 1.47, 95% confidence interval (CI) = 1.03-2.10, p = 0.04). No statistically significant association was demonstrated between presence of hyperdense sign and good functional outcome (OR = 1.04, 95% CI: 0.72-1.49, p = 0.85) or symptomatic intracranial hemorrhage sICH (OR: 1.80, 95% CI 0.72-4.47, p = 0.21) | ||
| 520 | |a CONCLUSIONS: This meta-analysis demonstrated that pre-intervention hyperdense sign on CT imaging might be useful in prediction of successful recanalization after MT | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Review | |
| 650 | 4 | |a Stroke | |
| 650 | 4 | |a hyperdesne vessel sign | |
| 650 | 4 | |a successful recanalization | |
| 700 | 1 | |a Aladamat, Nameer |e verfasserin |4 aut | |
| 700 | 1 | |a Samara, Mohammad |e verfasserin |4 aut | |
| 700 | 1 | |a Mierzwa, Adam T |e verfasserin |4 aut | |
| 700 | 1 | |a Ali, Ahsan |e verfasserin |4 aut | |
| 700 | 1 | |a Zaidi, Syed |e verfasserin |4 aut | |
| 700 | 1 | |a Jumaa, Mouhammad |e verfasserin |4 aut | |
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