Autoimmune thrombotic thrombocytopenic purpura associated with disseminated sarcoidosis : A case report
© 2024 The Authors. eJHaem published by British Society for Haematology and John Wiley & Sons Ltd..
Sarcoidosis is an inflammatory disease known to be associated with multiple autoimmune disorders. There is a restricted number of descriptions of the association between sarcoidosis and autoimmune thrombotic thrombocytopenic purpura (aTTP). We present the case of a 63-year-old woman admitted to the hospital to investigate a possible sarcoidosis who had hemolytic anemia and thrombocytopenia, with low ADAMTS13 activity and anti-ADAMTS13 antibodies, leading to a diagnosis of aTTP. Sarcoidosis was later confirmed and the two conditions evolved separately after 6 months, questioning the link between them. Clinicians should be aware of this rare cause of thrombocytopenia in patients with sarcoidosis, as aTTP is a life-threatening condition.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2024 |
|---|---|
| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:5 |
|---|---|
| Enthalten in: |
EJHaem - 5(2024), 1 vom: 21. Feb., Seite 225-230 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Billotte, Maxime [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
ADAMTS13 antibodies |
|---|
| Anmerkungen: |
Date Revised 27.02.2024 published: Electronic-eCollection Citation Status PubMed-not-MEDLINE |
|---|
| doi: |
10.1002/jha2.848 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM368965112 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM368965112 | ||
| 003 | DE-627 | ||
| 005 | 20240229165031.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 240229s2024 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1002/jha2.848 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1309.xml |
| 035 | |a (DE-627)NLM368965112 | ||
| 035 | |a (NLM)38406537 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Billotte, Maxime |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Autoimmune thrombotic thrombocytopenic purpura associated with disseminated sarcoidosis |b A case report |
| 264 | 1 | |c 2024 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Revised 27.02.2024 | ||
| 500 | |a published: Electronic-eCollection | ||
| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a © 2024 The Authors. eJHaem published by British Society for Haematology and John Wiley & Sons Ltd. | ||
| 520 | |a Sarcoidosis is an inflammatory disease known to be associated with multiple autoimmune disorders. There is a restricted number of descriptions of the association between sarcoidosis and autoimmune thrombotic thrombocytopenic purpura (aTTP). We present the case of a 63-year-old woman admitted to the hospital to investigate a possible sarcoidosis who had hemolytic anemia and thrombocytopenia, with low ADAMTS13 activity and anti-ADAMTS13 antibodies, leading to a diagnosis of aTTP. Sarcoidosis was later confirmed and the two conditions evolved separately after 6 months, questioning the link between them. Clinicians should be aware of this rare cause of thrombocytopenia in patients with sarcoidosis, as aTTP is a life-threatening condition | ||
| 650 | 4 | |a Case Reports | |
| 650 | 4 | |a ADAMTS13 antibodies | |
| 650 | 4 | |a case report | |
| 650 | 4 | |a sarcoidosis | |
| 650 | 4 | |a thrombotic thrombocytopenic purpura | |
| 700 | 1 | |a Eszto, Peter |e verfasserin |4 aut | |
| 700 | 1 | |a Thomas, Benoît |e verfasserin |4 aut | |
| 700 | 1 | |a Groizard, Pierre |e verfasserin |4 aut | |
| 700 | 1 | |a Perez, Pierre |e verfasserin |4 aut | |
| 700 | 1 | |a Campagne, Julien |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t EJHaem |d 2020 |g 5(2024), 1 vom: 21. Feb., Seite 225-230 |w (DE-627)NLM314118454 |x 2688-6146 |7 nnns |
| 773 | 1 | 8 | |g volume:5 |g year:2024 |g number:1 |g day:21 |g month:02 |g pages:225-230 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1002/jha2.848 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 5 |j 2024 |e 1 |b 21 |c 02 |h 225-230 | ||